E50000
Ethyl trifluoroacetate
99%
Synonym(s):
Trifluoroacetic acid ethyl ester
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Linear Formula:
CF3COOC2H5
CAS Number:
Molecular Weight:
142.08
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
206-851-6
Beilstein/REAXYS Number:
1761411
MDL number:
Assay:
99%
Form:
liquid
Quality Level
assay
99%
form
liquid
refractive index
n20/D 1.307 (lit.)
bp
60-62 °C (lit.)
density
1.194 g/mL at 25 °C (lit.)
SMILES string
CCOC(=O)C(F)(F)F
InChI
1S/C4H5F3O2/c1-2-9-3(8)4(5,6)7/h2H2,1H3
InChI key
STSCVKRWJPWALQ-UHFFFAOYSA-N
Related Categories
Application
Ethyl trifluoroacetate can be used:
- To synthesize cyclopentenones or furans containing trifluoromethyl group from aromatic ynones.
- In the selective trifluoroacetylation of anilines catalyzed by 4-dimethylaminopyridine.
- As a starting material in the two-step electrosynthesis of trifluoroacetyltrimethylsilane (CF3COSiMe3).
- In the preparation of trifluoromethyl ketones via trifluoroacetic ester/ketone metathesis with alkyl aryl ketones.
- To synthesize o-fluorinated trifluoro acetophenones from substituted fluorobenzene.
signalword
Danger
Storage Class
3 - Flammable liquids
flash_point_f
30.2 °F - closed cup
flash_point_c
-1 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves
hcodes
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2
Regulatory Information
危险化学品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Synthesis of 4-(Trifluoromethyl) cyclopentenones and 2-(Trifluoromethyl) furans by Reductive Trifluoroacetylation of Ynones
Zhang T and Maekawa H
Organic Letters, 19(24), 6602-6605 (2017)
Qi Zhang et al.
Journal of biophotonics, 11(6), e201700339-e201700339 (2018-01-18)
Targeting cyclooxygenase-2 (COX-2) for molecular imaging is an attractive approach applicable for its overexpression in inflammation and many malignancies. Herein, for monitoring COX-2, we synthesize a specific COX-2 probe celecoxib-MPA probe (CMP), based on celecoxib and a water-soluble near-infrared dye
Heike Gerhardt et al.
Journal of chromatography. A, 1428, 280-291 (2015-06-20)
A panel of methods of general suitability for complete structural elucidation of the stereochemistry of cyclopeptides, depsipeptides and lipopeptides is presented and described in detail. The suitability of the proposed methods was exemplified on the lipopeptide poaeamide from Pseudomonas poae.
Highly selective trifluoroacetic ester/ketone metathesis: an efficient approach to trifluoromethyl ketones and esters
Zhou Y, et al.
Tetrahedron, 70(31), 4668-4674 (2014)
Non-defluorinative electrochemical silylation of ethyl trifluoroacetate: a practical synthesis of trifluoroacetyltrimethylsilane via its ethyltrimethylsilyl ketal
Bordeau M, et al.
Tetrahedron Letters, 44(19), 3741-3744 (2003)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| V800189-6X500ML | 04061837891816 |
| 15512-1L-R | 04061838741912 |
| 15512-2.5L-R | 04061838125125 |
| 252549-100ML | 04061837886225 |
| 252549-1L | 04061837886249 |
| 252549-2.5L | 04061837889943 |
| 252549-4L | 04061837886263 |
| 252549-4X100ML | 04061837886270 |
| 252549-500ML | 04061837886294 |
| 252549-6X1L | 04061837886317 |
| 252549-6X500ML | 04061825973449 |
| 1040031000 | 04022536046174 |
| 11-0720-5-500ML-J | 04061837741012 |
| 11-0730-5-500ML-J | 04061837741029 |
| 47608-1L-F | 04061832362021 |
| 47608-250ML-F | 04061832362038 |
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service