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Merck
CN

A17900

Sigma-Aldrich

N-Acetyl-DL-methionine

ReagentPlus®, 99%

Synonym(s):

Methionamine

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About This Item

Linear Formula:
CH3SCH2CH2CH(NHCOCH3)CO2H
CAS Number:
Molecular Weight:
191.25
Beilstein:
1867673
EC Number:
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22
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product line

ReagentPlus®

Assay

99%

form

powder or crystals

reaction suitability

reaction type: solution phase peptide synthesis

color

white

mp

117-119 °C (lit.)

application(s)

peptide synthesis

SMILES string

CSCCC(NC(C)=O)C(O)=O

InChI

1S/C7H13NO3S/c1-5(9)8-6(7(10)11)3-4-12-2/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)

InChI key

XUYPXLNMDZIRQH-UHFFFAOYSA-N

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Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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S Pittelkow et al.
Protein expression and purification, 12(2), 269-276 (1998-03-31)
Aminoacylase I (EC 3.5.1.14) is one of the most abundant enzymes in the cortical region of mammalian kidney. Both the porcine and the human enzyme were overexpressed using baculovirus expression vector systems and purified by hydrophobic interaction chromatography and anion-exchange
Paul J Dierickx et al.
Alternatives to laboratory animals : ATLA, 30(1), 61-68 (2002-02-06)
Glutathione (GSH) plays a role in many toxicologically important metabolic processes. It was previously established that L-buthionine S,R-sulphoximine (BSO), a specific inhibitor of (- glutamylcysteine synthetase, reduces the GSH content more efficiently in rat (Fa32) than in human (HEp-G2) hepatoma-derived
K Lertratanangkoon et al.
Toxicology and applied pharmacology, 122(2), 191-199 (1993-10-01)
Bromobenzene (800 mg/kg, ip) caused severe liver necrosis with massive hemorrhage in the golden Syrian hamster within the first 24 hr. Kidney injury was also observed. Treatment with N-acetylmethionine (NAM) at an ip dose of 1200 mg/kg at 5 hr
R M Millis et al.
Nutrition and cancer, 31(1), 49-55 (1998-07-31)
Previous studies have shown that alteration of the dietary arginine-methionine balance by use of synthetic L-amino acids inhibits tumor growth of a subcutaneously transplanted Morris hepatoma at the expense of maintaining body weight. However, L-methionine is susceptible to degradation and
Kevin M Williams et al.
Journal of inorganic biochemistry, 99(11), 2119-2126 (2005-09-01)
The reaction of N-acetylmethionine (N-AcMet) with the complex [Pt(Et(2)en)(D(2)O)(2)](2+) (Et(2)en=N,N-diethylethylenediamine) was studied by NMR spectroscopy and molecular mechanics calculations. Complexes containing two methionine residues coordinated to the platinum atom were calculated to be relatively high in energy unless the bulk

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