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Merck
CN

A38207

2-Aminoacetophenone hydrochloride

99%

Synonym(s):

ω-Aminoacetophenone hydrochloride, Phenacylamine hydrochloride

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About This Item

Linear Formula:
C6H5COCH2NH2 · HCl
CAS Number:
Molecular Weight:
171.62
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
226-787-2
Beilstein/REAXYS Number:
3563173
MDL number:
Assay:
99%
Form:
crystals
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Product Name

2-Aminoacetophenone hydrochloride, 99%

InChI key

CVXGFPPAIUELDV-UHFFFAOYSA-N

InChI

1S/C8H9NO.ClH/c9-6-8(10)7-4-2-1-3-5-7;/h1-5H,6,9H2;1H

SMILES string

Cl.NCC(=O)c1ccccc1

assay

99%

form

crystals

mp

194 °C (dec.) (lit.)

Quality Level

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Frank Sporkert et al.
Forensic science international, 133(1-2), 39-46 (2003-05-14)
A sensitive and reproducible method for the quantitative determination of cathinone (CTN), norpseudoephedrine (NPE, cathine) and norephedrine (NE) from hair was developed. The compounds were extracted for 4 hours with phosphate buffer pH 2.0, followed by a standard solid phase
M J Bossard et al.
The Journal of biological chemistry, 265(10), 5640-5647 (1990-04-05)
A mechanism for beta-chlorophenethylamine inhibition of dopamine beta-monooxygenase has been postulated in which bound alpha-aminoacetophenone is generated followed by an intramolecular redox reaction to yield a ketone-derived radical cation as the inhibitory species (Mangold, J.B., and Klinman, J.P. (1984) J.
[Anorexigenic activity of various derivatives of alpha-aminoacetophenone].
M S Sánchez et al.
Archivos de farmacologia y toxicologia, 5(3), 165-168 (1979-12-01)
Dopamine beta-hydroxylase: activity and inhibition in the presence of beta-substituted phenethylamines.
J P Klinman et al.
Biochemistry, 21(1), 67-75 (1982-01-05)
Yasumasa Iwai et al.
Chemical & pharmaceutical bulletin, 50(3), 441-443 (2002-03-26)
The new coupling reaction of phenacylamines with silylstannane and lithium diisopropylamide (LDA) is reported. The treatment of a phenacylamine iodide 1 with (trimethylsilyl)tributylstannane (Me3SiSnBu3) and cesium fluoride (CsF) gave a dimerization product 2 having no iodine atom. Reaction of 1

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