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A72405

2-Amino-1-phenylethanol

Name: 2-Amino-1-phenylethanol
Brand: ALDRICH

98%

Synonym(s):

α-(Aminomethyl)benzyl alcohol, DL-β-Hydroxyphenethylamine, Phenylethanolamine

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About This Item

Linear Formula:

NH₂CH₂CH(OH)C₆H₅

CAS Number:

7568-93-6

Molecular Weight:

137.18

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24891194

EC Number:

231-469-1

Beilstein/REAXYS Number:

971222

MDL number:

MFCD00008137

Assay:

98%

Form:

solid

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Quality Level

100

assay

98%

form

solid

bp

160 °C/17 mmHg (lit.)

mp

56-58 °C (lit.)

SMILES string

NCC(O)c1ccccc1

InChI

1S/C8H11NO/c9-6-8(10)7-4-2-1-3-5-7/h1-5,8,10H,6,9H2

InChI key

ULSIYEODSMZIPX-UHFFFAOYSA-N

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Structural, mutagenic, and kinetic analysis of the binding of substrates and inhibitors of human phenylethanolamine N-methyltransferase.

Qian Wu et al.

Journal of medicinal chemistry, 48(23), 7243-7252 (2005-11-11)

The X-ray structure of human phenylethanolamine N-methyltransferase (hPNMT) complexed with its product, S-adenosyl-L-homocysteine (4), and the most potent inhibitor reported to date, SK&F 64139 (7), was used to identify the residues involved in inhibitor binding. Four of these residues, Val53

Limited potentiation of blood pressure response to oral tyramine by brain-selective monoamine oxidase A-B inhibitor, TV-3326 in conscious rabbits.

M Weinstock et al.

Neuropharmacology, 43(6), 999-1005 (2002-11-09)

TV-3326 is a novel cholinesterase inhibitor that produces irreversible brain-selective inhibition of monoamine oxidase (MAO)-A and B and has antidepressant-like activity in rats after chronic oral administration. This study determined whether TV-3326 would cause less potentiation than other irreversible MAO-inhibitors

Synthesis and structure-activity relationships of long-acting beta2 adrenergic receptor agonists incorporating arylsulfonamide groups.

Panayiotis A Procopiou et al.

Journal of medicinal chemistry, 52(8), 2280-2288 (2009-03-26)

A series of saligenin alkoxyalkylphenylsulfonamide beta(2) adrenoceptor agonists were prepared by reacting a protected saligenin oxazolidinone with alkynyloxyalkyl bromides, followed by Sonogashira reaction, hydrogenation, and deprotection. The meta-substituted primary sulfonamide was more potent than the para- and the ortho-analogues. Primary

Dissection of peripheral and central endogenous opioid modulation of systemic interleukin-1beta responses using c-fos expression in the rat brain.

K M Buller et al.

Neuropharmacology, 49(2), 230-242 (2005-07-05)

In opiate addicts or patients receiving morphine treatment, it has been reported that the immune system is often compromised. The mechanisms responsible for the adverse effects of opioids on responses to infection are not clear but it is possible that

Catecholamine-synthesizing enzymes in the adult and prenatal human testis.

Michail S Davidoff et al.

Histochemistry and cell biology, 124(3-4), 313-323 (2005-07-30)

Catecholamines play functional roles in the mature and developing mammalian testis but the cell types responsible for their local synthesis are still controversially discussed. Here, we demonstrate that four enzymes involved in the biosynthesis of catecholamines, namely, tyrosine hydroxylase (TH)

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Global Trade Item Number

SKU	GTIN
A72405-50G	04061832281469
A72405-10G	04061833383896

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