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A76001

(±)-3-Amino-1,2-propanediol

Name: (±)-3-Amino-1,2-propanediol
Brand: ALDRICH

97%

Synonym(s):

(±)-3-Amino-1,2-dihydroxypropane, 1-Aminoglycerol, 2,3-Dihydroxypropan-1-amine, 3-Amino-2-hydroxypropanol

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About This Item

Linear Formula:

NH₂CH₂CH(OH)CH₂OH

CAS Number:

616-30-8

Molecular Weight:

91.11

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24891256

EC Number:

210-475-8

Beilstein/REAXYS Number:

1719121

MDL number:

MFCD00008140

Assay:

97%

Form:

liquid

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Properties

Quality Level

200

assay

97%

form

liquid

refractive index

n20/D 1.492 (lit.)

bp

264-265 °C/739 mmHg (lit.)

density

1.175 g/mL at 25 °C (lit.)

SMILES string

NCC(O)CO

InChI

1S/C3H9NO2/c4-1-3(6)2-5/h3,5-6H,1-2,4H2

InChI key

KQIGMPWTAHJUMN-UHFFFAOYSA-N

Description

Application

(±)-3-Amino-1,2-propanediol is used as a reactant in the synthesis of lipid-like delivery molecules(lipidoids) for RNA interference (RNAi) therapeutics. It is also used in the synthesis of the bioactive template to prepare cationic α-helical polypeptides and various cationic polymers for gene delivery.

pictograms

GHS05

signalword

Danger

hcodes

H314

pcodes

P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405

Hazard Classifications

Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 2

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Competitive inhibition of lipolytic enzymes. II. Preparation of 'monoacylamino' phospholipids.

R Dijkman et al.

Biochimica et biophysica acta, 1043(1), 67-74 (1990-03-12)

This paper describes the synthesis of a number of phosphatidylcholines and phosphatidylglycols, in which one fatty acyl ester group is replaced by an acylamino function. The phospholipids, both of the alpha- and beta-type, are prepared in racemic and enantiomeric pure

A specific receptor site for glycerol, a new sweet tastant for Drosophila: structure-taste relationship of glycerol in the labellar sugar receptor cell.

Takaya Koseki et al.

Chemical senses, 29(8), 703-711 (2004-10-07)

Glycerol, a linear triol, is a sweet tastant for mammals but it has not previously been recognized to stimulate the sense of taste in insects. Here we show by electrophysiological experimentation that it effectively stimulates the labellar sugar receptor cell

Conversion of a hemoglobin alpha chain aspartate(47) ester to N-(2,3-dihydroxypropyl)asparagine as a method for identification of the principal binding site for benzo[a]pyrene anti-diol epoxide.

B W Day et al.

Chemical research in toxicology, 4(3), 359-363 (1991-05-01)

Human hemoglobin was alkylated with (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene (BPDE) and then treated with aqueous (+/-)-3-amino-1,2-propanediol to convert alkylated carboxyl side chains to N-(2,3-dihydroxypropyl) amides. Tryptic peptides produced from the modified protein were subjected to affinity chromatography on phenylboronic

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Global Trade Item Number

SKU	GTIN
A76001-5G	04061837634925
A76001-25G	04061833385296
A76001-100G	04061837634918