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Merck
CN

A80807

2-Amino-2-thiazoline

97%

Synonym(s):

2-Thiazolin-2-amine

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About This Item

Empirical Formula (Hill Notation):
C3H6N2S
CAS Number:
Molecular Weight:
102.16
EC Number:
217-224-1
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
105367
MDL number:
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InChI

1S/C3H6N2S/c4-3-5-1-2-6-3/h1-2H2,(H2,4,5)

InChI key

REGFWZVTTFGQOJ-UHFFFAOYSA-N

SMILES string

NC1=NCCS1

assay

97%

mp

79-82 °C (lit.)

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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J J Díaz Gil et al.
Revista espanola de oncologia, 29(4), 615-621 (1982-01-01)
Some aspects of the effect of thioproline and 2-amino-thiazoline-HCl on HeLa cell cultures are studied. Both drugs, at 1 mM concentrations, produce morphological changes that become stabilized after four days. The morphology changes depend on the microtubules, microfilaments, and de
Reverse transformation agent and their ability to complex metal ions.
Z X Huang et al.
European journal of cancer & clinical oncology, 17(10), 1151-1152 (1981-10-01)
M J Pine et al.
Journal of medicine, 14(5-6), 433-449 (1983-01-01)
2--amino-2-thiazoline (AT) and 1-thiazolidine-4-carboxylate (TC, thioproline), which have been previously proposed as agents of reverse transformation, have been examined as antitumor agents in several rodent tumor systems. AT administration reduced tumor incidence in sym-dimethylhydrazine treated outbred ICR Swiss female mice
[Mechanisms of the radioprotective effect of 2-amino-2-thiazoline in experiments on yeasts].
L T Zolotareva
Radiobiologiia, 22(2), 257-258 (1982-03-01)
Preliminary clinical results with norgamem (thioproline) and revercan (2-amino-2-thiazoline): the first inducers of reverse transformation.
A Brugarolas et al.
Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 80, 346-350 (1982-01-01)

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