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B10102

Benzo[e]pyrene

Name: Benzo[<I>e</I>]pyrene
Brand: ALDRICH

98%

Synonym(s):

1,2-Benzpyrene, 4,5-Benzpyrene

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About This Item

Empirical Formula (Hill Notation):

C₂₀H₁₂

CAS Number:

192-97-2

Molecular Weight:

252.31

UNSPSC Code:

12352103

NACRES:

NA.23

PubChem Substance ID:

24891539

EC Number:

205-892-7

Beilstein/REAXYS Number:

1911334

MDL number:

MFCD00003605

Assay:

98%

Form:

crystals

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Properties

Quality Level

100

assay

98%

form

crystals

mp

177-180 °C (lit.)

SMILES string

c1ccc2c(c1)c3cccc4ccc5cccc2c5c34

InChI

1S/C20H12/c1-2-8-16-15(7-1)17-9-3-5-13-11-12-14-6-4-10-18(16)20(14)19(13)17/h1-12H

InChI key

TXVHTIQJNYSSKO-UHFFFAOYSA-N

Description

General description

This polycyclic aromatic hydrocarbon is soluble in acetone. It is a non-carcinogenic benzopyrene isomer. Studies report its lack of immunosuppressive activity following in vivo and in vitro exposure.In nature, it is metabolized by strains of C. elegans to 3-benzo[e]Pyrene sulphate, 1-hydroxy-3-benzi[e]pyrenyl sulfate and bezo[e]Pyrene 3-O-β-glucopyranoside.

Application

Used for studies of immune suppressive activity of bezo[e]Pyrene on antibody response to DNP-Ficoll and sheep erythrocytes and "dispersive liquid -liquid micro extraction” technique by extracting organic compounds from water samples.

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pictograms

GHS08,GHS09

signalword

Danger

hcodes

H350,H410

pcodes

P201 - P273 - P308 + P313

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Determination of organic compounds in water using dispersive liquid-liquid microextraction.

Mohammad Rezaee et al.

Journal of chromatography. A, 1116(1-2), 1-9 (2006-04-01)

A new microextraction technique termed dispersive liquid-liquid microextraction (DLLME) was developed. DLLME is a very simple and rapid method for extraction and preconcentration of organic compounds from water samples. In this method, the appropriate mixture of extraction solvent (8.0 microL

Direct suppression of in vitro antibody production by mouse spleen cells by the carcinogen benzo(a)pyrene but not by the noncarcinogenic congener benzo(e)pyrene.

K L White et al.

Cancer research, 44(8), 3388-3393 (1984-08-01)

The role of metabolic activation of benzo(a)pyrene B(a)P in mediating its suppression of humoral immune responsiveness of the female C57BL/6 X C3H F1 (hereafter called B6C3F1) mouse was addressed in these studies. The model was the in vitro antibody response

Inhibition of apoptosis in human retinal pigment epithelial cells treated with benzo(e)pyrene, a toxic component of cigarette smoke.

Saffar Mansoor et al.

Investigative ophthalmology & visual science, 51(5), 2601-2607 (2009-12-05)

To study the inhibitory effects of some agents or drugs (inhibitors) on benzo(e)pyrene (B(e)P)-induced cell death and apoptosis on human retinal pigment epithelial (ARPE-19) cells in vitro. ARPE-19 cells were pretreated with varying concentrations of different classes of inhibitors (calpain

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Global Trade Item Number

SKU	GTIN
B10102-100MG	04061833420119
B10102-25MG	04061832940298