C4080
Cyheptamide
Synonym(s):
10,11-Dihydro-5H-dibenzo(a,d)cycloheptene-5-carboxamide
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About This Item
Empirical Formula (Hill Notation):
C16H15NO
CAS Number:
Molecular Weight:
237.30
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
form
powder
Quality Level
SMILES string
NC(=O)C1c2ccccc2CCc3ccccc13
InChI
1S/C16H15NO/c17-16(18)15-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)15/h1-8,15H,9-10H2,(H2,17,18)
InChI key
APBVLLORZMAWKI-UHFFFAOYSA-N
Application
Used to study pharmacological activity involved in identification of compounds with central nervous system activity
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Anticonvulsant activities and brain concentrations of cyheptamide and carbamazepine.
G H Wimbish et al.
Proceedings of the Western Pharmacology Society, 23, 75-79 (1980-01-01)
Jeannine M Conway et al.
Biomedical chromatography : BMC, 26(9), 1071-1076 (2012-01-10)
Topiramate (Topamax®) is an antiepileptic medication used as adjunctive and monotherapy in patients with epilepsy and for migraine prophylaxis. A GC-MS assay was developed that was capable of detecting topiramate plasma concentrations following a single rectal or oral dose administration.
Josefin Koehn et al.
Antimicrobial agents and chemotherapy, 59(11), 6682-6688 (2015-08-08)
In the treatment of HIV infection, a combination of anti-HIV drugs is commonly used in highly active antiretroviral therapy (HAART). One such combination recommended for clinical therapy consists of the two HIV protease inhibitors atazanavir and ritonavir and the HIV
[Determination of plasma lidocaine by gas-liquid chromatography].
I Saavedra et al.
Revista medica de Chile, 115(7), 661-664 (1987-07-01)
P W Codding et al.
Journal of medicinal chemistry, 27(5), 649-654 (1984-05-01)
The molecular structures of cyheptamide and 3-hydroxy-3- phenacyloxindole were determined by X-ray diffraction methods. The amide group in both compounds exhibits delocalization of the pi-electrons over the three atoms (N, C, and O), while the bond linking the amide to
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