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C59408

Sigma-Aldrich

4-Chloro-3-nitrobenzenesulfonyl chloride

96%

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About This Item

Linear Formula:
ClC6H3(NO2)SO2Cl
CAS Number:
Molecular Weight:
256.06
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

96%

form

powder

mp

59-60 °C (lit.)

SMILES string

[O-][N+](=O)c1cc(ccc1Cl)S(Cl)(=O)=O

InChI

1S/C6H3Cl2NO4S/c7-5-2-1-4(14(8,12)13)3-6(5)9(10)11/h1-3H

InChI key

SEWNAJIUKSTYOP-UHFFFAOYSA-N

Application

4-Chloro-3-nitrobenzenesulfonyl chloride can be used:
  • In the preparation of functionalized 1H-indenes via copper-catalyzed arylative cyclization.
  • As a precursor in the synthesis of N-arylsulfonyl-3-acylindole arylcarbonyl hydrazone derivatives that show potential nematicidal activity.
  • As a key starting material in the synthesis of sulfonamide analogs of ferrostatin-1 (fer-1), which possess good ferroptosis inhibition property.
  • In the synthesis of 4-chloro-3-nitrobenzene thiol.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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