C59408
4-Chloro-3-nitrobenzenesulfonyl chloride
96%
Sign Into View Organizational & Contract Pricing
Select a Size
About This Item
Linear Formula:
ClC6H3(NO2)SO2Cl
CAS Number:
Molecular Weight:
256.06
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Assay
96%
form
powder
mp
59-60 °C (lit.)
SMILES string
[O-][N+](=O)c1cc(ccc1Cl)S(Cl)(=O)=O
InChI
1S/C6H3Cl2NO4S/c7-5-2-1-4(14(8,12)13)3-6(5)9(10)11/h1-3H
InChI key
SEWNAJIUKSTYOP-UHFFFAOYSA-N
Application
4-Chloro-3-nitrobenzenesulfonyl chloride can be used:
- In the preparation of functionalized 1H-indenes via copper-catalyzed arylative cyclization.
- As a precursor in the synthesis of N-arylsulfonyl-3-acylindole arylcarbonyl hydrazone derivatives that show potential nematicidal activity.
- As a key starting material in the synthesis of sulfonamide analogs of ferrostatin-1 (fer-1), which possess good ferroptosis inhibition property.
- In the synthesis of 4-chloro-3-nitrobenzene thiol.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
Storage Class Code
8A - Combustible corrosive hazardous materials
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Novel ferroptosis inhibitors with improved potency and ADME properties.
Hofmans, Sam et al.
Journal of Medicinal Chemistry, 59(5), 2041-2053 (2016)
A simple, fast and chemoselective method for the preparation of arylthiols.
Bellale, Eknath V et al.
Synthesis, 2009(19), 3211-3213 (2009)
Synthesis and quantitative structure-activity relationship (QSAR) study of novel N-arylsulfonyl-3-acylindole arylcarbonyl hydrazone derivatives as nematicidal agents.
Che, Zhiping et al.
Journal of Agricultural and Food Chemistry, 61(24), 5696-5705 (2013)
Xiaoming Zeng et al.
Journal of the American Chemical Society, 133(44), 17638-17640 (2011-10-13)
A variety of polysubstituted 1H-indenes can be prepared through the copper-catalyzed arylative cyclization of simple arylalkynes with commercially available aromatic sulfonyl chlorides that function as an aryl group donor. The reaction tolerates a broad range of functional groups, including bromide
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service