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Merck
CN

CDS021585

[2-Amino-3-(4-bromobenzoyl)phenyl]acetic acid

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About This Item

Empirical Formula (Hill Notation):
C15H12BrNO3
CAS Number:
Molecular Weight:
334.16
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
Form:
solid
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InChI

1S/C15H12BrNO3/c16-11-6-4-9(5-7-11)15(20)12-3-1-2-10(14(12)17)8-13(18)19/h1-7H,8,17H2,(H,18,19)

SMILES string

NC1=C(C=CC=C1C(C2=CC=C(C=C2)Br)=O)CC(O)=O

InChI key

ZBPLOVFIXSTCRZ-UHFFFAOYSA-N

description

AldrichCPR

form

solid

Gene Information

Other Notes

Please note that Sigma-Aldrich provides this product to early discovery researchers as part of a collection of unique chemicals. Sigma-Aldrich does not collect analytical data for this product. Buyer assumes responsibility to confirm product identity and/or purity. All sales are final.
NOTWITHSTANDING ANY CONTRARY PROVISION CONTAINED IN SIGMA-ALDRICH′S STANDARD TERMS AND CONDITIONS OF SALE OR AN AGREEMENT BETWEEN SIGMA-ALDRICH AND BUYER, SIGMA-ALDRICH SELLS THIS PRODUCT "AS-IS" AND MAKES NO REPRESENTATION OR WARRANTY WHATSOEVER WITH RESPECT TO THIS PRODUCT, INCLUDING ANY (A) WARRANTY OF MERCHANTABILITY, (B) WARRANTY OF FITNESS FOR A PARTICULAR PURPOSE, OR (C) WARRANTY AGAINST INFRINGEMENT OF INTELLECTUAL PROPERTY RIGHTS OF A THIRD PARTY, WHETHER ARISING BY LAW, COURSE OF DEALING, COURSE OF PERFORMANCE, USAGE OF TRADE OR OTHERWISE.

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Skull and crossbones

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Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Constantine D Georgakopoulos et al.
Retina (Philadelphia, Pa.), 37(2), 388-395 (2016-07-22)
To evaluate the analgesic effect of bromfenac, a topically administered nonsteroidal antiinflammatory agent, in patients undergoing intravitreal injections (IVIs) of anti-vascular endothelial growth factor agents. A single center, prospective, randomized, double-blind, placebo-controlled, cross over interventional study. Patients scheduled to undergo
Andrés Fernández-Vega Cueto et al.
International ophthalmology, 41(2), 707-717 (2020-10-26)
To assess the effectiveness, safety and predictability of femtosecond laser-assisted cataract surgery (FLACS) in eyes with shallow anterior chamber (AC). This is a prospective consecutive clinical study. All eyes presented an anterior chamber depth (ACD) ≤ 2.1 mm and were submitted to FLACS
Idaira Sánchez-Santos et al.
Experimental eye research, 194, 108020-108020 (2020-03-27)
There is a need to find alternative treatments for MEe. Bromfenac has shown promise in inhibiting the COX-2 enzymatic pathway that partially causes the inflammatory cascade which contributes to the precipitation of ME. However, like other NSAID's, its intraocular half-life
Keith A Walter et al.
Arquivos brasileiros de oftalmologia, 83(1), 55-61 (2019-10-31)
To evaluate the rate of cystoid macular edema development among cataract surgery patients on four different therapeutic regimens. The present study is a retrospective analysis of 5,380 eyes following uncomplicated phacoemulsification at Wake Forest University. The study period went from
Marco Coassin et al.
Advances in therapy, 36(10), 2712-2722 (2019-09-05)
To compare the efficacy of bromfenac 0.09% and dexamethasone 0.1% in the treatment of anterior chamber inflammation after uncomplicated cataract surgery. Seventy-six patients with senile cataracts and no other ocular comorbidities who underwent uneventful phacoemulsification were randomized 1:1 to receive

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