CF0018
Pyrazolyltetrafluorobromoethane
form
liquid
reaction suitability
reaction type: C-C Bond Formation
Application
Pyrazolyltetrafluorobromoethane is a fluoroalkylbromide that is a radical source of the pyrazolyl tetrafluoroethyl moiety. Alternatively, it can be also selectively metallated at the fluorinated carbon with Turbo Grignard reagent at low temperatures and the resulting thermally unstable anion can act as a nucleophilic fluoroalkylation reagent towards a wide variety of electrophiles, such as aldehydes, ketones or sulfonylimines.
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Legal Information
Product of CF Plus Chemicals.
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Articles
Fluoroalkylation toolbox expands with various reagents for late-stage fluoroalkylation in organic synthesis and medicinal chemistry.
目前的氟烷基化工具包括Togni试剂、高价碘全氟烷基化试剂、氟烷基溴化物、硅烷类和羧酸盐类以及用于后期氟烷基化的磺酰氟类。
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