CF0022
Phenylsulfanyltetrafluoroethyl trimethylsilane
form
liquid
reaction suitability
reaction type: C-C Bond Formation
Application
After being activated with silicophilic activators, like fluorides, alkoxides or carboxylates, phenylsulfanyltetrafluoroethyl trimethylsilane acts as nucleophilic phenylsulfanyltetrafluoroethylation reagent towards electrophiles such as aromatic aldehydes. A phenylsulfanyltetrafluoroethyl moiety incorporated in the substrate can be treated with tributyltin hydride and generate the corresponding fluoroalkyl radical. If the substrate lacks any olefins, it can be reduced to tetrafluoroethyl group whereas if the substrate contains an olefin in the correct spatial orientation, it can lead to an intramolecular cyclization affording tetrafluorinated cyclic structures.
Automate your fluorination reactions with Synple Automated Synthesis Platform (SYNPLE-SC002)
Automate your fluorination reactions with Synple Automated Synthesis Platform (SYNPLE-SC002)
Legal Information
Product of CF Plus Chemicals.
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Articles
Fluoroalkylation toolbox expands with various reagents for late-stage fluoroalkylation in organic synthesis and medicinal chemistry.
目前的氟烷基化工具包括Togni试剂、高价碘全氟烷基化试剂、氟烷基溴化物、硅烷类和羧酸盐类以及用于后期氟烷基化的磺酰氟类。
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service