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Merck
CN

CF0023

Sigma-Aldrich

4-Bromophenoxytetrafluoethyl trimethylsilane

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About This Item

Linear Formula:
C11H13BrF4OSi
CAS Number:
MDL number:
UNSPSC Code:
12352101
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form

liquid

reaction suitability

reaction type: C-C Bond Formation

Application

After being activated with silicophilic activators, like fluorides, alkoxides or carboxylates, 4-bromophenoxytetrafluoroethyl trimethylsilane serves as a nucleophilic source of the 4-bromophenoxytetrafluoroethyl moiety in reaction with electrophiles such as aromatic aldehydes. The aromatic bromide can be used to build up molecular complexity using Pd-catalyzed cross couplings.

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Legal Information

Product of CF Plus Chemicals.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Articles

Fluoroalkylation toolbox expands with various reagents for late-stage fluoroalkylation in organic synthesis and medicinal chemistry.

目前的氟烷基化工具包括Togni试剂、高价碘全氟烷基化试剂、氟烷基溴化物、硅烷类和羧酸盐类以及用于后期氟烷基化的磺酰氟类。

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