CF0034
4-Bromophenoxytetrafluoroethanesulphonyl fluoride
form
liquid
reaction suitability
reaction type: C-C Bond Formation
InChI
1S/C8H4BrF5O3S/c9-5-1-3-6(4-2-5)17-7(10,11)8(12,13)18(14,15)16/h1-4H
InChI key
SPXWBVPRFLQEGR-UHFFFAOYSA-N
Application
4-Bromophenoxytetrafluoroethanesulfonyl fluoride serves as a moderately reactive 4-bromophenoxytetrafluoroethanesulfonylation reagent. Fluoroalkylsulfonylation of the amine nitrogen greatly lowers the pKa value of the N-H and can be used to modulate the behaviour of the drug candidate or build additional molecular complexity around the highly acidic fluoroalkylsulfonamide nitrogen.
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Legal Information
Product of CF Plus Chemicals.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
Storage Class Code
8A - Combustible corrosive hazardous materials
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Fluoroalkylation toolbox expands with various reagents for late-stage fluoroalkylation in organic synthesis and medicinal chemistry.
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