D143359
Dansyl chloride
98%
Synonym(s):
5-(Dimethylamino)naphthalene-1-sulfonyl chloride, DNSCl
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About This Item
Empirical Formula (Hill Notation):
C12H12ClNO2S
CAS Number:
Molecular Weight:
269.75
EC Number:
210-092-6
UNSPSC Code:
12352100
MDL number:
Beilstein/REAXYS Number:
2217205
InChI
1S/C12H12ClNO2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3
InChI key
XPDXVDYUQZHFPV-UHFFFAOYSA-N
SMILES string
CN(C)c1cccc2c(cccc12)S(Cl)(=O)=O
assay
98%
mp
72-74 °C (lit.)
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Application
A fluorogenic reagent for fluorescent N-terminal derivatization of amino acids and peptides and detection by reverse phase HPLC.
Reagent for fluorescent labeling of amines, amino acids, proteins, and phenols.
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Chemical & Pharmaceutical Bulletin, 37, 2841-2841 (1989)
Cristina Avonto et al.
Toxicology and applied pharmacology, 289(2), 177-184 (2015-10-13)
Skin sensitization is an important toxicological end-point in the risk assessment of chemical allergens. Because of the complexity of the biological mechanisms associated with skin sensitization, integrated approaches combining different chemical, biological and in silico methods are recommended to replace
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