D178454
Dimethyl phosphite
98%
Synonym(s):
Dimethoxyphosphine oxide, Dimethyl hydrogen phosphite, Dimethyl hydrogen phosphonate, Dimethyl phosphonate, Hydrogen dimethyl phosphite
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Linear Formula:
(CH3O)2P(O)H
CAS Number:
Molecular Weight:
110.05
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
212-783-8
Beilstein/REAXYS Number:
1697490
MDL number:
Assay:
98%
Form:
liquid
Quality Level
assay
98%
form
liquid
impurities
≤0.5% trimethyl phosphate, ≤1% methyl alcohol
refractive index
n20/D 1.402 (lit.)
bp
170-171 °C (lit.)
density
1.2 g/mL at 25 °C (lit.)
SMILES string
[H]P(=O)(OC)OC
InChI
1S/C2H7O3P/c1-4-6(3)5-2/h6H,1-2H3
InChI key
HZCDANOFLILNSA-UHFFFAOYSA-N
Application
Dimethyl phosphite may be used as an effective alternative to organic tin hydrides as radical reducing agents for organic halides, thionoesters, and isocyanides to form the corresponding hydrocarbons. Radical translocation/cyclization reactions of terminal alkynes to form cyclic phosphonates can also be effectively carried using dimethyl phosphite as a reagent under tin-free condition.
Dimethyl phosphite is used in the synthesis of α-aminophosphonates, which are medicinally important phosphorus analogs of amino acids, by treating with an amine and an aldehyde or a ketone. It can also be employed in asymmetric hydrophosphonylation of aldehydes to synthesize optically active α-hydroxy phosphonates.
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 3 - Carc. 2 - Muta. 2 - Skin Sens. 1
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
158.0 °F - closed cup
flash_point_c
70 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Regulatory Information
监管及禁止进口产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Zirconium (IV) compounds as efficient catalysts for synthesis of α-aminophosphonates.
Bhagat S and Chakraborti A K
The Journal of Organic Chemistry, 73(15), 6029-6032 (2008)
Microwave-assisted solvent-free and catalyst-free Kabachnik?Fields reactions for α-amino phosphonates.
Mu X J, et al.
Tetrahedron Letters, 47(7), 1125-1127 (2006)
I Pastirk et al.
The journal of physical chemistry. A, 109(11), 2413-2416 (2006-07-13)
Multidimensional chemical detection and identification based on phase shaped femtosecond laser pulses coupled to mass spectrometry is demonstrated. The method based on binary phase shaping (BPS) takes into account the accuracy and precision standards required by analytical chemistry. It couples
Global Trade Item Number
| SKU | GTIN |
|---|---|
| D178454-500G | 04061833560747 |
| D178454-25G | 04061833560730 |