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Merck
CN

D2762

(Dansylaminoethyl)­tri­methyl­ammonium perchlorate

Synonym(s):

(5-Dimethylamino­naphthalene-1-sulfon­amido­ethyl)­tri­methyl­ammonium perchlorate, DASP

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About This Item

Empirical Formula (Hill Notation):
C17H26N3O2S · ClO4
CAS Number:
Molecular Weight:
435.92
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352005
MDL number:
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InChI key

JALGRPFYCOBGHM-UHFFFAOYSA-M

SMILES string

[O-]Cl(=O)(=O)=O.CN(C)c1cccc2c(cccc12)S(=O)(=O)NCC[N+](C)(C)C

InChI

1S/C17H26N3O2S.ClHO4/c1-19(2)16-10-6-9-15-14(16)8-7-11-17(15)23(21,22)18-12-13-20(3,4)5;2-1(3,4)5/h6-11,18H,12-13H2,1-5H3;(H,2,3,4,5)/q+1;/p-1

form

solid

reaction suitability

reagent type: oxidant

storage temp.

−20°C

Application

  • Used as a guest for multivalent macrocyclic hosts in histone surface recognition
  • Dye for fluorescence spectroscopy
Fluorescent probe for receptor proteolipid from electric organ of Electrophorus electricus

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signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Hugo R Arias et al.
Biochemistry, 45(7), 2014-2026 (2006-02-16)
We investigated the molecular mechanisms and the binding site location for the fluorophor crystal violet (CrV), a noncompetitive antagonist of the nicotinic acetylcholine receptor (AChR). To this end, radiolabeled competition binding, fluorescence spectroscopy, Schild-type analysis, patch-clamp recordings, and molecular dynamics
A Szatanik-Kloc et al.
Plant physiology and biochemistry : PPB, 120, 194-201 (2017-10-22)
It is widely believed that pectin are responsible for the vast majority of cation binding positions in the root cell walls. To estimate the role of particular kinds of pectin, we studied the cell wall material isolated from the roots
Agonists of Torpedo nicotinic receptors: essential role of a positive charge.
A Y Jeng et al.
Annals of the New York Academy of Sciences, 358, 370-373 (1980-01-01)
R Narayanan et al.
International journal of peptide and protein research, 17(2), 170-180 (1981-02-01)
The interaction of the cholinergic fluorescent probes, 1-(5-dimethyl-aminoaphthalene-1-sulfonamido) ethane-2-trimethylammonium perchlorate, 1-(5-dimethylaminoaphthalene-1-sulfonamido) pentane-5-trimethylammonium tartarate and 1-(5-dimethylaminonaphthalene-1-sulfonamido) decane-10- trimethylammonium tartarate with horse serum cholinesterase has been examined by fluorescence and n.m.r. methods. Fluorescence titrations show binding of the decane derivative to two
The use of a cholinergic fluorescent probe for the study of the receptor proteolipid.
G Weber et al.
Molecular pharmacology, 7(5), 530-537 (1971-09-01)

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