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Merck
CN

D60400

2,3-Dichloro-5,6-dicyano-p-benzoquinone

98%

Synonym(s):

4,5-Dichloro-3,6-dioxo-1,4-cyclohexadiene-1,2-dicarbonitrile, DDQ

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About This Item

Empirical Formula (Hill Notation):
C8Cl2N2O2
CAS Number:
Molecular Weight:
227.00
UNSPSC Code:
12352117
NACRES:
NA.22
PubChem Substance ID:
EC Number:
201-542-2
Beilstein/REAXYS Number:
747939
MDL number:
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Product Name

2,3-Dichloro-5,6-dicyano-p-benzoquinone, 98%

InChI key

HZNVUJQVZSTENZ-UHFFFAOYSA-N

InChI

1S/C8Cl2N2O2/c9-5-6(10)8(14)4(2-12)3(1-11)7(5)13

SMILES string

ClC1=C(Cl)C(=O)C(C#N)=C(C#N)C1=O

assay

98%

form

powder

reaction suitability

reagent type: oxidant

mp

210-215 °C (dec.) (lit.)

storage temp.

2-8°C

Quality Level

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Application

2,3-Dichloro-5,6-dicyano-p-benzoquinone (DDQ) can be used as:
  • A deprotecting reagent for a variety of compounds, such as thioacetals, acetals, and ketals.
  • An electron-transfer reagent for the synthesis of quinolines from imines and alkynes or alkenes.
  • An effective reagent for the benzylic and allylic C−H functionalization.
  • An oxidizing agent for the synthesis of functionalized furans and benzofurans.
  • A reagent with Ph3P in an efficient synthesis of 1,2-benzisoxazoles.

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

supp_hazards

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

危险化学品
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A novel method for the highly efficient synthesis of 1,2-benzisoxazoles under neutral conditions using the Ph3P/DDQ system
Iranpoor N, et al.
Tetrahedron Letters, 47, 8247-8247 (2006)
Solvent-Free One-Step Photochemical Hydroxylation of Benzene Derivatives by the Singlet Excited State of 2, 3-Dichloro-5, 6-dicyano-p-benzoquinone Acting as a Super Oxidant.
Ohkubo K, et al.
Chemistry?A European Journal , 21(7), 2855-2861 (2015)
Deprotection of benzyl ethers using 2, 3-dichloro-5, 6-dicyano-p-benzoquinone (DDQ) under photoirradiation.
Rahim MA, et al.
Tetrahedron Letters, 46(43), 7307-7309 (2005)
Mild and efficient photochemical and thermal deprotection of thioacetals and ketals using DDQ
Mathew L and Sankararaman S
The Journal of Organic Chemistry, 58, 7576-7576 (1993)
DDQ-mediated formation of carbon? carbon bonds: Oxidation of imines
Bortolotti B, et al.
Tetrahedron, 49, 10157-10157 (1993)

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