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Merck
CN

D67200

2,3-Dichloro-1,4-naphthoquinone

98%

Synonym(s):

Dichlon

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About This Item

Empirical Formula (Hill Notation):
C10H4Cl2O2
CAS Number:
Molecular Weight:
227.04
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
204-210-5
Beilstein/REAXYS Number:
1073511
MDL number:
Assay:
98%
Form:
powder
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InChI key

SVPKNMBRVBMTLB-UHFFFAOYSA-N

InChI

1S/C10H4Cl2O2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H

SMILES string

ClC1=C(Cl)C(=O)c2ccccc2C1=O

assay

98%

form

powder

mp

194-197 °C (lit.)

pictograms

Skull and crossbonesEnvironment

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

农药列管产品
危险化学品
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Ibrahim A Darwish
Journal of AOAC International, 88(1), 38-45 (2005-03-12)
Three simple and sensitive spectrophotometric methods were developed and validated for determination of the hydrochloride salts of fluoxetine, sertraline, and paroxetine in their pharmaceutical dosage forms. These methods were based on the reaction of the N-alkylvinylamine formed from the interaction
C A Pritsos et al.
Biochemical pharmacology, 35(7), 1131-1135 (1986-04-01)
Dietary exposure of rats to a high concentration of 2,3-dichloro-1,4-naphthoquinone (CNQ) (2 g/kg diet) for 60 days altered cardiac mitochondrial function and activities of anti-oxidant enzymes in hepatic and cardiac tissue. CNQ moderately depressed the cardiac mitochondrial respiratory control ratio
C A Pritsos et al.
Biochemical pharmacology, 33(23), 3771-3777 (1984-12-01)
The addition of 2,3-dichloro-1,4-naphthoquinone (CNQ) to substrate-depleted, GSH-supplemented rat liver mitochondria resulted in a dose-dependent depletion of reactable suflhydryl groups and a concomitant increase in mitochondrial disulfide content at a ratio of 2 thiols depleted/disulfide generated. The molar ratio of
C A Pritsos et al.
Research communications in chemical pathology and pharmacology, 42(2), 271-280 (1983-11-01)
The addition of 2,3-dichloro-1,4-naphthoquinone (CNQ) to isolated mitochondria supplemented with GSSG resulted in a respiratory burst with the production of O2- and H2O2, and a decrease in the level of measurable disulfide. Superoxide generated by the xanthine oxidase system or
Inhibition of liver glycolysis in rats by dietary dichlone (2,3-dichloro-1,4-naphthoquinone).
C A Pritsos et al.
Bulletin of environmental contamination and toxicology, 35(1), 23-28 (1985-07-01)

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