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Merck
CN

D80800

Sigma-Aldrich

N,N′-Dicyclohexylurea

98%

Synonym(s):

1,3-Dicyclohexylurea

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About This Item

Linear Formula:
C6H11NHCONHC6H11
CAS Number:
2387-23-7
Molecular Weight:
224.34
EC Number:
219-213-7
MDL number:
MFCD00003829
UNSPSC Code:
12352100
PubChem Substance ID:
24894186
NACRES:
NA.22

Key Documents

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Quality Level

100

Assay

98%

form

solid

mp

232-233 °C (lit.)

SMILES string

O=C(NC1CCCCC1)NC2CCCCC2

InChI

1S/C13H24N2O/c16-13(14-11-7-3-1-4-8-11)15-12-9-5-2-6-10-12/h11-12H,1-10H2,(H2,14,15,16)

InChI key

ADFXKUOMJKEIND-UHFFFAOYSA-N

Gene Information

human ... EPHX2(2053)
mouse ... Ephx2(13850)

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000456251
0000456251
0000451647
0000451647
0000441211

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Mozhgan Aghajanzadeh et al.
International journal of pharmaceutics, 586, 119546-119546 (2020-06-17)
In the present study, we successfully synthesized nanocarriers (NCs) based on Y-shaped miktoarm copolymers, Poly Ethylene Glycol-Lysine-(Poly Caprolactone)2 (PEG-Lys-PCL2), which were loaded by baicalein (B) through the nanoprecipitation process to assess their in-vitro and in-vivo properties. We applied various methods
Stevan Pecic et al.
Bioorganic & medicinal chemistry letters, 22(1), 601-605 (2011-11-15)
Inhibition of soluble epoxide hydrolase (sEH) has been proposed as a new pharmaceutical approach for treating hypertension and vascular inflammation. The most potent sEH inhibitors reported in literature to date are urea derivatives. However, these compounds have limited pharmacokinetic profiles.
Xiang Fang et al.
American journal of physiology. Heart and circulatory physiology, 290(1), H55-H63 (2005-08-23)
Epoxyeicosatrienoic acids (EETs), lipid mediators synthesized from arachidonic acid by cytochrome P-450 epoxygenases, are converted by soluble epoxide hydrolase (SEH) to the corresponding dihydroxyeicosatrienoic acids (DHETs). Originally considered as inactive degradation products of EETs, DHETs have biological activity in some
L Mark Hall et al.
Journal of chemical information and modeling, 52(5), 1222-1237 (2012-04-12)
The goal of many metabolomic studies is to identify the molecular structure of endogenous molecules that are differentially expressed among sampled or treatment groups. The identified compounds can then be used to gain an understanding of disease mechanisms. Unfortunately, despite
T Watanabe et al.
Analytical biochemistry, 299(2), 227-234 (2001-12-04)
A rapid and reliable electrospray tandem mass spectrometric method for soluble epoxide hydrolase (sEH) inhibitors in rat hepatic microsomes is described. Four synthesized sEH inhibitors were extracted from rat hepatic microsomes with ethyl acetate and were determined by HPLC using
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