D80800
N,N′-Dicyclohexylurea
98%
Synonym(s):
1,3-Dicyclohexylurea
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About This Item
Linear Formula:
C6H11NHCONHC6H11
CAS Number:
Molecular Weight:
224.34
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
219-213-7
MDL number:
Assay:
98%
Form:
solid
InChI key
ADFXKUOMJKEIND-UHFFFAOYSA-N
InChI
1S/C13H24N2O/c16-13(14-11-7-3-1-4-8-11)15-12-9-5-2-6-10-12/h11-12H,1-10H2,(H2,14,15,16)
SMILES string
O=C(NC1CCCCC1)NC2CCCCC2
assay
98%
form
solid
mp
232-233 °C (lit.)
Quality Level
Gene Information
human ... EPHX2(2053)
mouse ... Ephx2(13850)
Related Categories
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Z Yu et al.
Circulation research, 87(11), 992-998 (2000-11-25)
The cytochrome P450-derived epoxyeicosatrienoic acids (EETs) have potent effects on renal vascular reactivity and tubular sodium and water transport; however, the role of these eicosanoids in the pathogenesis of hypertension is controversial. The current study examined the hydrolysis of the
Stevan Pecic et al.
Bioorganic & medicinal chemistry letters, 22(1), 601-605 (2011-11-15)
Inhibition of soluble epoxide hydrolase (sEH) has been proposed as a new pharmaceutical approach for treating hypertension and vascular inflammation. The most potent sEH inhibitors reported in literature to date are urea derivatives. However, these compounds have limited pharmacokinetic profiles.
Mozhgan Aghajanzadeh et al.
International journal of pharmaceutics, 586, 119546-119546 (2020-06-17)
In the present study, we successfully synthesized nanocarriers (NCs) based on Y-shaped miktoarm copolymers, Poly Ethylene Glycol-Lysine-(Poly Caprolactone)2 (PEG-Lys-PCL2), which were loaded by baicalein (B) through the nanoprecipitation process to assess their in-vitro and in-vivo properties. We applied various methods
Julian Dominik Wolf et al.
Journal of colloid and interface science, 566, 234-241 (2020-02-02)
Lysine based cationic surfactants are well-tolerated tools for hydrophobic ion pairing (HIP) with DNA and its incorporation into lipophilic delivery systems. Di-Boc-lysine was esterified with 1-hexadecanol and the Boc-residues were cleaved off resulting in hexadecyl lysinate (HL). Subsequently, its Log
Xiang Fang et al.
American journal of physiology. Heart and circulatory physiology, 290(1), H55-H63 (2005-08-23)
Epoxyeicosatrienoic acids (EETs), lipid mediators synthesized from arachidonic acid by cytochrome P-450 epoxygenases, are converted by soluble epoxide hydrolase (SEH) to the corresponding dihydroxyeicosatrienoic acids (DHETs). Originally considered as inactive degradation products of EETs, DHETs have biological activity in some
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