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Merck
CN

E1055

Epichlorohydrin

99%

Synonym(s):

(±)-Epichlorohydrin, (±)-2-(Chloromethyl)oxirane, 1-Chloro-2,3-epoxypropane

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About This Item

Empirical Formula (Hill Notation):
C3H5ClO
CAS Number:
106-89-8
Molecular Weight:
92.52
EC Number:
203-439-8
UNSPSC Code:
12352100
PubChem Substance ID:
24894383
Beilstein/REAXYS Number:
79785
MDL number:
MFCD00005132

Key Documents

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InChI key

BRLQWZUYTZBJKN-UHFFFAOYSA-N

InChI

1S/C3H5ClO/c4-1-3-2-5-3/h3H,1-2H2

SMILES string

ClCC1CO1

vapor density

3.2 (vs air)

vapor pressure

13.8 mmHg ( 21.1 °C)

assay

99%

autoignition temp.

779 °F

expl. lim.

21 %

bp

115-117 °C (lit.)

mp

−57 °C (lit.)

density

1.183 g/mL at 25 °C (lit.)

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Repr. 2 - Skin Corr. 1B - Skin Sens. 1

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

82.4 °F

flash_point_c

28 °C

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCBG6507V
BCBG0892V
SHBB6792V
SHBB6794V
SHBB6793V

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Karnkamol Trisopon et al.
Pharmaceutics, 12(6) (2020-06-11)
A new co-processed, rice starch-based excipient (CS) was developed via a spray-drying technique. Native rice starch (RS) was suspended in aqueous solutions of 10%-15% cross-linked carboxymethyl rice starch (CCMS) and 0.5%-6.75% silicon dioxide (in the form of sodium silicate), before
A K Giri
Mutation research, 386(1), 25-38 (1997-03-01)
Epichlorohydrin (ECH) is one of the more commercially important aliphatic epoxides used extensively as an industrial intermediate, a laboratory reagent, and as an insecticide. It is a volatile, colourless liquid with an ethereal odour. It behaves as an alkylating agent.
An evaluation of the genetic toxicity of epichlorohydrin. A report of an expert group of the International Commission for Protection against Environmental Mutagens and Carcinogens.
R J Srám et al.
Mutation research, 87(3), 299-319 (1981-11-01)
Swetha Inturi et al.
ACS nano, 9(11), 10758-10768 (2015-10-22)
Notwithstanding rapid advances of nanotechnology in diagnostic imaging and drug delivery, the engineered nanocarriers still exhibit substantial lack of hemocompatibility. Thus, when injected systemically, nanoparticles are avidly recognized by blood leukocytes and platelets, but the mechanisms of immune recognition are
Jingyun Wang et al.
Biomacromolecules, 13(2), 559-564 (2012-01-20)
The stability of a paper-immobilized antibody was investigated over a range of temperatures (40-140 °C) and relative humidities (RH, 30-90%) using both unmodified filter paper and the same paper impregnated with polyamide-epichlorohydrin (PAE) as supports. Antibody stability decreased with increasing
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