Key Documents

View All Documentation

E35400

Ethyl 2-methylacetoacetate

Name: Ethyl 2-methylacetoacetate
Brand: ALDRICH

90%

Synonym(s):

Ethyl 2-methyl-3-oxobutanoate

Select a Size

Change View

About This Item

Linear Formula:

CH₃COCH(CH₃)CO₂C₂H₅

CAS Number:

609-14-3

Molecular Weight:

144.17

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24894520

EC Number:

210-179-9

Beilstein/REAXYS Number:

1071742

MDL number:

MFCD00009164

Assay:

90%

Form:

liquid

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Quality Level

200

assay

90%

form

liquid

refractive index

n20/D 1.418 (lit.)

bp

187 °C (lit.)

density

1.019 g/mL at 25 °C (lit.)

SMILES string

CCOC(=O)C(C)C(C)=O

InChI

1S/C7H12O3/c1-4-10-7(9)5(2)6(3)8/h5H,4H2,1-3H3

InChI key

FNENWZWNOPCZGK-UHFFFAOYSA-N

Description

Application

Ethyl 2-methylacetoacetate is used as a substrate in the rhenium-catalyzed synthesis of multisubstituted aromatic compounds.
It can be employed in the synthesis of coumarin derivatives via Pechmann condensation.
It undergoes dehydration to yield conjugated alkynyl and allenyl esters.
It is also used in the total synthesis of chlorotonil A, yangjinhualine A, (+)- and (−)-saudin.

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

145.4 °F - closed cup

flash_point_c

63 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Concise, regiocontrolled synthesis of yangjinhualine A.

Boukouvalas J and McCann L C

Tetrahedron Letters, 52(11), 1202-1204 (2011)

An enantioselective total synthesis of (+)-and (−)-saudin. Determination of the absolute configuration.

Boeckman R K, et al.

Journal of the American Chemical Society, 124(2), 190-191 (2002)

Selective One-Pot Synthesis of Allenyl and Alkynyl Esters from β-Ketoesters.

Maity P and Lepore S D

The Journal of Organic Chemistry, 74(1), 158-162 (2008)

View All Related Papers

Global Trade Item Number

SKU	GTIN
E35400-25G	04061833603345
E35400-100G	04061831836110