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Merck
CN

E45260

Woodward′s reagent K

95%

Synonym(s):

2-Ethyl-5-phenylisoxazolium-3′-sulfonate, NEPIS

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About This Item

Empirical Formula (Hill Notation):
C11H11NO4S
CAS Number:
Molecular Weight:
253.27
UNSPSC Code:
12352005
NACRES:
NA.22
PubChem Substance ID:
EC Number:
223-988-7
Beilstein/REAXYS Number:
4149224
MDL number:
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InChI

1S/C11H11NO4S/c1-2-12-7-6-11(16-12)9-4-3-5-10(8-9)17(13,14)15/h3-8H,2H2,1H3

InChI key

MWOOKDULMBMMPN-UHFFFAOYSA-N

SMILES string

CC[n+]1ccc(o1)-c2cccc(c2)S([O-])(=O)=O

assay

95%

reaction suitability

reaction type: Coupling Reactions

mp

220 °C (dec.) (lit.)

application(s)

peptide synthesis

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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S R Rao et al.
Indian journal of biochemistry & biophysics, 34(3), 253-258 (1997-06-01)
Maize leaf NADP-malic enzyme was rapidly inactivated by micromolar concentrations of Woodward's reagent K (WRK). The inactivation followed pseudo-first order reaction kinetics. The order of reaction with respect to WRK was 1, suggesting that inactivation was a consequence of the
Paulina Nawłoka et al.
Acta biochimica Polonica, 50(2), 567-572 (2003-07-02)
Effects of several chemical probes selectively modifying various amino-acid residues on the activity of UDP-glucose : solasodine glucosyltransferase from eggplant leaves was studied. It was shown that diethylpyrocarbonate (DEPC), a specific modifier of histidine residues, was strongly inhibitory. However, in
G Feller et al.
The Journal of biological chemistry, 271(39), 23836-23841 (1996-09-27)
Chloride is the allosteric effector of vertebrate pancreatic and salivary alpha-amylases and of the bacterial alpha-amylase from Alteromonas haloplanctis. Activation experiments of A. haloplanctis alpha-amylase by several monovalent anions show that a negative charge, not restricted to that of Cl-
Jongchan Woo et al.
Protein science : a publication of the Protein Society, 17(4), 725-735 (2008-03-25)
Renilla luciferase (RLUC) is a versatile tool for gene expression assays and in vivo biosensor applications, but its catalytic mechanism remains to be elucidated. RLUC is evolutionarily related to the alpha/beta hydrolase family. Its closest known homologs are bacterial dehalogenases
W Feng et al.
Molecular membrane biology, 13(2), 85-93 (1996-04-01)
In this work we show that ryanodine binding to junctional sarcoplasmic reticulum (SR) membranes or purified ryanodine receptor (RyR) is inhibited in a time- and concentration-dependent fashion by prior treatment with the carboxyl reagent dicyclohexylcarbodiimide (DCCD). Exposure of the membrane-bound

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