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Merck
CN

E8260

Ethoxyquin

≥75% (capillary GC)

Synonym(s):

1,2-Dihydro-6-ethoxy-2,2,4-trimethylquinoline, 6-Ethoxy-1,2-dihydro-2,2,4-trimethylquinoline

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About This Item

Empirical Formula (Hill Notation):
C14H19NO
CAS Number:
Molecular Weight:
217.31
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
202-075-7
Beilstein/REAXYS Number:
158223
MDL number:
Assay:
≥75% (capillary GC)
Form:
liquid
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Product Name

Ethoxyquin, ≥75% (capillary GC)

InChI key

DECIPOUIJURFOJ-UHFFFAOYSA-N

InChI

1S/C14H19NO/c1-5-16-11-6-7-13-12(8-11)10(2)9-14(3,4)15-13/h6-9,15H,5H2,1-4H3

SMILES string

CCOc1ccc2NC(C)(C)C=C(C)c2c1

assay

≥75% (capillary GC)

form

liquid

density

1.03 g/mL at 20 °C (lit.)

Quality Level

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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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Rex Munday et al.
Chemico-biological interactions, 155(3), 140-147 (2005-07-28)
Reduction of naphthoquinones by DT-diaphorase is often described as a detoxification reaction. This is true for some naphthoquinone derivatives, such as alkyl and di-alkyl naphthoquinones, but the situation with other substances, such as 2-hydroxy-1,4-naphthoquinone, is more complex. In the present
Alina Błaszczyk et al.
Acta poloniae pharmaceutica, 62(2), 111-115 (2005-09-16)
In our study ethoxyquin (EQ) and its two complexes with flavonoids were obtained from ethoxyquin (1,2-dihydro-6-ethoxy-2,2,4-trimethylquinoline, EQ) and quercetin (EQ-Q, 1:1) or rutin (EQ-R, 1:1). Cytotoxicity of the tested compounds was studied using the trypan blue exclusion method and the
Alina Błaszczyk et al.
Chemico-biological interactions, 162(1), 70-80 (2006-06-27)
2,2,4,7-Tetramethyl-1,2,3,4-tetrahydroquinoline (THQ) is a new synthetic compound with potential antioxidant activity. In this study, cytotoxic, genotoxic and antioxidant activities of THQ were studied on human lymphocytes with the use of the trypan blue exclusion assay, the TUNEL method, the comet
Yoichi Aoki et al.
Journal of AOAC International, 93(1), 277-283 (2010-03-26)
An analytical method using HPLC with fluorescence detection (HPLC-FL) has been developed and applied for the survey of residue levels of ethoxyquin in a variety of food products of animal origin. HPLC was performed using a silica octadecylsilane column, butylhydroxytoluene-acetonitrile-water
Ronald A Lubet et al.
Chemico-biological interactions, 182(1), 22-28 (2009-08-22)
Identifying agents that block tumor initiation is a goal of cancer prevention. The ability of a chemically varied group of agents to induce various drug metabolizing genes in livers of rats was examined. Sprague-Dawley rats were treated for 7 days

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