Skip to Content
Merck
CN

F505

Fisetin

Synonym(s):

3,3′,4′,7-Tetra­hydroxy­flavone, 5-Deoxyquercetin, Natural Brown 1

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C15H10O6 · xH2O
CAS Number:
345909-34-4
Molecular Weight:
286.24 (anhydrous basis)
EC Number:
208-434-4
UNSPSC Code:
12352100
PubChem Substance ID:
24894880
Beilstein/REAXYS Number:
292829
MDL number:
MFCD04220857

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI key

GYHFUROKCOMWNQ-UHFFFAOYSA-N

InChI

1S/C15H10O6.H2O/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7;/h1-6,16-18,20H;1H2

SMILES string

O.Oc1ccc2C(=O)C(O)=C(Oc2c1)c3ccc(O)c(O)c3

mp

>330 °C (lit.)

Gene Information

human ... CDC2(983), CDK5(1020), CDK6(1021), CYP1A2(1544), GSK3A(2931)
mouse ... Hexa(15211)
rat ... Il4(287287), Tnf(24835)

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
09227AG
08225LI
08011PQ
04327JT
07728CI

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Jing Li et al.
Basic & clinical pharmacology & toxicology, 115(4), 321-329 (2014-03-22)
Intravesical chemotherapy after transurethral resection has been widely used as an adjuvant therapy to prevent recurrence and progression of superficial bladder cancer. Due to the insufficiency of the current chemotherapeutics, there is an urgent need to search for more novel
Yewseok Suh et al.
Carcinogenesis, 30(2), 300-307 (2008-11-28)
Overexpression of cyclooxygenase 2 (COX2) and uncontrolled wingless and Int (Wnt)-signaling pathway have long been suggested to play crucial roles in colorectal cancer. Studies show that selective COX2 inhibitors possess great potential as chemopreventive agents for colon cancer. Recent studies
Ragini Sinha et al.
European journal of medicinal chemistry, 79, 102-109 (2014-04-15)
Flavonols are an important class of naturally occurring molecules and are known for their pharmacological activity. The activity is associated with the ability of flavonols to influence membrane-dependent processes. We have investigated the in-vitro anti-proliferative and anti-oxidant activity of galangin
Stephanie Lemmo Ham et al.
Integrative biology : quantitative biosciences from nano to macro, 7(7), 792-800 (2015-06-30)
Cell migration is a major process that drives metastatic progression of cancers, the major cause of cancer death. Existing chemotherapeutic drugs have limited efficacy to prevent and/or treat metastasis, emphasizing the need for new treatments. We focus on triple negative
C U F Kelly Hill et al.
Cancer chemotherapy and pharmacology, 76(1), 179-185 (2015-05-29)
TMFol (3',4',5'-trimethoxyflavonol) is a synthetic analogue of the naturally occurring flavonol fisetin and quercetin, which have been considered of potential usefulness in the management of prostate cancer. We investigated whether TMFol may have preclinical features superior to those of its
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service