G4802
DL-Glyceraldehyde, dimer
95%
Synonym(s):
3,6-Dihydroxy-1,4-dioxane-2,5-dimethanol
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About This Item
Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
Molecular Weight:
180.16
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
95%
Quality Level
assay
95%
mp
144-145 °C (lit.)
storage temp.
2-8°C
SMILES string
OC[C@H]1O[C@@H](O)[C@H](CO)O[C@@H]1O
InChI
1S/2C3H6O3/c2*4-1-3(6)2-5/h2*1,3,5-6H,2H2
InChI key
NGNVWCSFFIVLAR-UHFFFAOYSA-N
General description
DL-Glyceraldehyde , dimer, a dimeric form of DL-glyceraldehyde is an organic compound that possesses a symmetrical p-dioxan crystalline structure with equatorially bonded hydroxy and hydroxymethyl groups. It reacts with a primary alkyl amine to form a Schiff base, during the synthesis of DL-alanine derivatives.
Application
- Aldehyde Reductase Activity: The enzymatic properties of DL-Glyceraldehyde dimer were examined in the context of aldehyde reductases from Euonymus japonica leaves, providing insights into the reduction processes of aldose sugars, which are significant for understanding stress responses in plants (Negm, 1986).
- Enzymatic Reductase Functions: DL-Glyceraldehyde dimer was studied in the purification and characterization of human liver aldehyde reductases, focusing on its role in metabolic detoxification, crucial for pharmaceutical applications involving drug metabolism and toxicity (Petrash and Srivastava, 1982).
- Protozoan Metabolic Pathways: The enzymatic characterization of aldehyde reductase from Crithidia fasciculata, with DL-Glyceraldehyde dimer as a substrate, provided insights into the metabolic pathways of protozoans, important for developing treatments against parasitic infections (Kobayashi, 1982).
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Experimental and Theoretical Study of the Products from the Spontaneous Dimerization of DL-and D-Glyceraldehyde
Federico G, et al.
Journal of the Brazilian Chemical Society, 16, 467-476 (2005)
Non-enzymatic transformation of dl-glyceraldehyde, 1, 3-dihydroxyacetone, and pyruvaldehyde with primary amine to the same dl-alanine derivatives
Yande H, et al.
Tetrahedron Letters, 56, 4516-4519 (2015)
Chan Mee Lee et al.
Archives of pharmacal research, 38(6), 1090-1098 (2014-10-16)
Aldose reductase (AR) is a key enzyme in the polyol pathway that is strongly implicated in the pathogenesis of diabetic complications. AR inhibitors have been proposed as therapeutic agents for diabetic complications through suppression of sorbitol formation and accumulation. In
Global Trade Item Number
| SKU | GTIN |
|---|---|
| G4802-1G | 04061825590516 |
| G4802-5G | 04061831826838 |