H23201
p-Coumaric acid
98%
Synonym(s):
trans-4-Hydroxycinnamic acid
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About This Item
Linear Formula:
HOC6H4CH=CHCO2H
CAS Number:
Molecular Weight:
164.16
UNSPSC Code:
12352103
Beilstein/REAXYS Number:
2207383
MDL number:
assay
98%
mp
214 °C (dec.) (lit.)
SMILES string
OC(=O)\C=C\c1ccc(O)cc1
InChI
1S/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12)/b6-3+
InChI key
NGSWKAQJJWESNS-ZZXKWVIFSA-N
Biochem/physiol Actions
Hydroxycinnamic acid found in many fruits and vegetables.
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Venkatesan Amalan et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 84, 230-236 (2016-09-24)
P-coumaric acid (p-CA, 3-[4-hydroxyphenyl]-2-propenoic acid), the major component widely found in nutritious plant foods, has various antioxidant, antiinflammatory and anticancer property. To evaluate the antidiabetic and antihyperlipidemic mechanisms, via the effects on carbohydrate, lipids and lipoproteins responses in adult male
Tristan Richard et al.
Bioorganic & medicinal chemistry, 19(10), 3152-3155 (2011-04-29)
Abnormal β-amyloid peptide accumulation and aggregation is considered to be responsible for the formation and cerebral deposition of senile plaques in the brains of patients with Alzheimer's disease (AD). Inhibition of the formation of β-amyloid (Aβ) fibrils would be an
Hisanori Hattori et al.
Bioorganic & medicinal chemistry, 19(18), 5392-5401 (2011-08-26)
The tumor microenvironment is characterized by hypoxia, low-nutrient levels, and acidosis. A natural product chemistry-based approach was used to discover small molecules that modulate adaptive responses to a hypoxic microenvironment through the hypoxia-inducible factor (HIF)-1 signaling pathways. Five compounds, such