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Merck
CN

I27902

Isoprenaline hydrochloride

98%

Synonym(s):

(±)-Isoproterenol hydrochloride, 1-(3′,4′-Dihydroxyphenyl)-2-isopropylaminoethanol hydrochloride, N-Isopropyl-DL-noradrenaline hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C11H17NO3 · HCl
CAS Number:
51-30-9
Molecular Weight:
247.72
EC Number:
200-089-8
UNSPSC Code:
12352200
MDL number:
MFCD00012603
Beilstein/REAXYS Number:
3917363

Key Documents

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InChI

1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H

InChI key

IROWCYIEJAOFOW-UHFFFAOYSA-N

SMILES string

Cl.CC(C)NCC(O)c1ccc(O)c(O)c1

assay

98%

mp

165-175 °C (dec.) (lit.)

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Biochem/physiol Actions

β-adrenoceptor agonist; increases cytosolic cAMP.

Storage Class

13 - Non Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
055K1021
08604DH
07808PE
S29322
01723LC

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Jiao Li et al.
PloS one, 8(3), e58334-e58334 (2013-03-28)
Here we investigate how ß-adrenergic stimulation of the heart alters regulation of ryanodine receptors (RyRs) by intracellular Ca(2+) and Mg(2+) and the role of these changes in SR Ca(2+) release. RyRs were isolated from rat hearts, perfused in a Langendorff
Sachin Nayyar et al.
American journal of physiology. Heart and circulatory physiology, 305(8), H1181-H1188 (2013-08-13)
QT variability (QTV) signifies repolarization lability, and increased QTV is a risk predictor for sudden cardiac death. The aim of the present study was to investigate the role of autonomic nervous system activity on QTV. This study was performed in
Michael Schwarzl et al.
Critical care medicine, 41(12), e401-e410 (2013-08-22)
We tested whether mild hypothermia impacts on circulatory and respiratory dysfunction during experimental endotoxemia. Randomized controlled prospective experimental study. Large animal facility, Medical University of Graz, Austria. Thirteen anesthetized and mechanically ventilated pigs. Lipopolysaccharide was administered for 4 hours. With
Sander Land et al.
Biophysical journal, 104(6), 1349-1356 (2013-03-27)
Previous studies on Serca2 knockout (KO) mice showed that cardiac function is sustained in vivo for several weeks after knockout, whereas SERCA protein levels decrease and calcium dynamics are significantly impaired. In this study, we reconcile observed cellular and organ
Zhan-Peng Huang et al.
Circulation research, 112(9), 1234-1243 (2013-03-26)
The adult heart is composed primarily of terminally differentiated, mature cardiomyocytes that express signature genes related to contraction. In response to mechanical or pathological stress, the heart undergoes hypertrophic growth, a process defined as an increase in cardiomyocyte cell size
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