I6806
Iodoacetic acid
98%
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About This Item
Linear Formula:
ICH2CO2H
CAS Number:
Molecular Weight:
185.95
EC Number:
200-590-1
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
1739079
InChI
1S/C2H3IO2/c3-1-2(4)5/h1H2,(H,4,5)
InChI key
JDNTWHVOXJZDSN-UHFFFAOYSA-N
SMILES string
OC(=O)CI
assay
98%
mp
77-79 °C (lit.)
Application
Enolic radical and ketene precursor. SH modifier.
Reagent for the modification of cysteine residues in proteins.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1A
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Regulatory Information
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Tetrahedron, 49, 8465-8465 (1993)
Tetrahedron, 50, 7579-7579 (1994)
R Nemani et al.
Archives of biochemistry and biophysics, 300(1), 24-29 (1993-01-01)
Chemical modification of the sulfhydryl residues of the catalytic subunits of protein phosphatases 1 and 2A was studied. Both enzymes were inactivated by a variety of thiol group reagents. Mercurial compounds were the most effective inactivators. Of the alkylating agents
Tatyana Y Samgina et al.
Journal of the American Society for Mass Spectrometry, 22(12), 2246-2255 (2011-10-08)
Mass spectrometry faces considerable difficulties in de novo sequencing of long non-tryptic peptides with S-S bonds. Long disulfide-containing peptides brevinins 1E and 2Ec from frog Rana ridibunda were reduced and alkylated with nine novel and three known derivatizing agents. Eight
Catherine E Ferland et al.
Phytotherapy research : PTR, 26(9), 1278-1285 (2012-09-28)
The aim of the present study was to evaluate whether eugenol, the main constituent of clove oil, has the capacity to provide analgesia in the monoiodoacetate-induced rat model of osteoarthritis. Animals (n = 6/group) received either eugenol (20 or 40 mg/kg) or a
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