I6806
Iodoacetic acid
98%
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About This Item
Linear Formula:
ICH2CO2H
CAS Number:
Molecular Weight:
185.95
EC Number:
200-590-1
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
1739079
InChI
1S/C2H3IO2/c3-1-2(4)5/h1H2,(H,4,5)
InChI key
JDNTWHVOXJZDSN-UHFFFAOYSA-N
SMILES string
OC(=O)CI
assay
98%
mp
77-79 °C (lit.)
Application
Enolic radical and ketene precursor. SH modifier.
Reagent for the modification of cysteine residues in proteins.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1A
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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Tetrahedron, 50, 7579-7579 (1994)
Tetrahedron, 49, 8465-8465 (1993)
R Nemani et al.
Archives of biochemistry and biophysics, 300(1), 24-29 (1993-01-01)
Chemical modification of the sulfhydryl residues of the catalytic subunits of protein phosphatases 1 and 2A was studied. Both enzymes were inactivated by a variety of thiol group reagents. Mercurial compounds were the most effective inactivators. Of the alkylating agents
X D Wang et al.
Journal of dental research, 92(10), 918-924 (2013-08-13)
Temporomandibular joint osteoarthritis (TMJOA) is clinically characterized by female preponderance, with a female-to-male ratio of more than 2:1; however, the underlying mechanism remains obscure. We examined the effects of estrogen on TMJOA induced by monosodium iodoacetate. Female rats were randomly
A C Ogbonna et al.
European journal of pain (London, England), 17(4), 514-526 (2012-11-22)
Osteoarthritis (OA) is a highly prevalent, age-related pain condition that poses a significant clinical problem. Here, in the monosodium iodoacetate (MIA) model of OA, we have characterized pain behaviours and associated changes at the first pain synapse in the dorsal
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