L020080
TCA Deblock
configured for MerMade, configured for PerkinElmer, configured for Polygen
type
for DNA synthesis
for DNA synthesis
product line
Proligo Reagents
storage condition
dry at room temperature
concentration
28-32 g/L (TCA content, titration)
impurities
≤200 ppm water content (Karl Fischer)
color
 clear
clear
compatibility
configured for MerMade
configured for PerkinElmer
configured for Polygen
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Preparation Note
Trichloroacetic acid / Dichloromethane 3/100 (v/v)
Other Notes
Deblock solution containing trichloroacetic acid (TCA) in dichloromethane removes the dimethoxytrityl (DMT) protecting group from the 5′hydroxyl moiety of nucleotides already incorporated into the growing nucleic acid, prior to the addition of the next phosphoramidite. Removal of the DMT allows the unprotected 5′hydroxyl moiety to react with a new phosphoramidite in a subsequent extension reaction.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 2 - Carc. 2 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
Target Organs
Central nervous system, Respiratory system
WGK
WGK 2
Regulatory Information
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