M14870
5-Methoxygramine
99%
Synonym(s):
3-(Dimethylaminomethyl)-5-methoxyindole, NSC 88885
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Empirical Formula (Hill Notation):
C12H16N2O
CAS Number:
Molecular Weight:
204.27
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
240-669-8
Beilstein/REAXYS Number:
170533
MDL number:
Assay:
99%
InChI key
GOERTRUXQHDLHC-UHFFFAOYSA-N
InChI
1S/C12H16N2O/c1-14(2)8-9-7-13-12-5-4-10(15-3)6-11(9)12/h4-7,13H,8H2,1-3H3
SMILES string
COc1ccc2[nH]cc(CN(C)C)c2c1
assay
99%
Application
- Reactant for preparation of dopamine D2 receptor antagonists
- Reactant for asymmetric preparation of ethenyl(tetrahydro)carbazoledicarboxylates via gold(I)-catalyzed intramolecular Friedel-Crafts allylic alkylation reaction
- Reactant for preparation of N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ols as dopamine D2-like receptor ligands
- Reactant for preparation of substituted N-trimethoxybenzoyl indoles, indolines, and a tetrahydroquinoline via N-aroylation with trimethoxybenzoyl chloride or anhydride as antitubulin agents
- Reactant for preparation of indolylmethanesulfonamide and its methoxy derivatives
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
B M Clancy et al.
The Journal of pharmacology and experimental therapeutics, 242(1), 108-114 (1987-07-01)
The kinetics of agonist and antagonist interactions with the 5-hydroxytryptamine2 receptor were studied in the isolated rabbit aorta by following the antagonist-induced decrease in the steady-state response to an agonist. A model describing the competitive drug-receptor interactions was fitted to
Mark G Devlin et al.
European journal of pharmacology, 498(1-3), 59-69 (2004-09-15)
The effect of ligand pretreatment on human 5-hydroxytryptamine2C (5-HT2C) receptors was examined in CHO cells expressing high (CHO-1C7; 67+/-3 pmol/mg) or low (CHO-1C19; 72+/-10 fmol/mg) levels of the receptor. Seventy-two hours pretreatment of CHO-1C7 cells with various ligands did not
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service