M1641
Methoxyphenamine hydrochloride
≥99%
Synonym(s):
2-Methoxy-N,α-dimethylbenzeneethanamine hydrochloride, NSC 65644
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About This Item
Empirical Formula (Hill Notation):
C11H17NO · HCl
CAS Number:
Molecular Weight:
215.72
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Quality Level
Assay
≥99%
drug control
regulated under CDSA - not available from Sigma-Aldrich Canada
SMILES string
Cl.CNC(C)Cc1ccccc1OC
InChI
1S/C11H17NO.ClH/c1-9(12-2)8-10-6-4-5-7-11(10)13-3;/h4-7,9,12H,8H2,1-3H3;1H
InChI key
FGSJNNQVSUVTPW-UHFFFAOYSA-N
Related Categories
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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S D Roy et al.
Clinical pharmacology and therapeutics, 38(2), 128-133 (1985-08-01)
Urine and plasma concentrations of methoxyphenamine (MP) and three of its metabolites were determined after a single oral 60.3 mg dose of MP hydrochloride to healthy subjects of known debrisoquin (D) phenotype. Urine was collected from five extensive (EM) and
Y Nakahara et al.
Forensic science international, 63(1-3), 109-119 (1993-12-01)
The excretion of methoxyphenamine (MOP) and methamphetamine (MA) into beards has been studied. Six healthy male subjects orally took 50 mg of MOP at a single dose and 7 doses for a successive 7 days. Their beard hairs were collected
Separation of optical isomers of methoxyphenamine and its metabolites as N-heptafluorobutyryl-L-prolyl derivatives by fused-silica capillary gas chromatography.
S D Roy et al.
Journal of chromatography, 431(1), 210-215 (1988-09-23)
Weili Wei et al.
Respirology (Carlton, Vic.), 15(5), 830-836 (2010-06-16)
Sequential three-step empirical therapy is useful for the management of chronic cough. The purpose of this study was to evaluate the efficacy and safety of modified sequential three-step empirical therapy. Consecutive patients (n = 240) with chronic cough were recruited
R T Coutts et al.
Drug metabolism and disposition: the biological fate of chemicals, 22(5), 756-760 (1994-09-01)
Metabolism of methoxyphenamine (MP) was conducted in vitro using commercially available microsomes prepared from human AHH-1 TK+/-cells in which CYP2D6 had been expressed. This study has confirmed the involvement of CYP2D6 in the metabolism of MP to O-desmethylmethoxyphenamine (ODMP) and
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