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Merck
CN

M26305

N-Methylacetamide

≥99%

Synonym(s):

Acetylmethylamine

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About This Item

Linear Formula:
CH3CONHCH3
CAS Number:
Molecular Weight:
73.09
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
201-182-6
Beilstein/REAXYS Number:
1071255
MDL number:
Assay:
≥99%
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Quality Level

assay

≥99%

refractive index

n20/D 1.433 (lit.)

bp

204-206 °C (lit.)

mp

26-28 °C (lit.)

density

0.957 g/mL at 25 °C (lit.)

SMILES string

CNC(C)=O

InChI

1S/C3H7NO/c1-3(5)4-2/h1-2H3,(H,4,5)

InChI key

OHLUUHNLEMFGTQ-UHFFFAOYSA-N

Application

N-Methylacetamide can be used:
  • To synthesize N-methyl-N-(3-thienyl)acetamide by reacting with 3-bromothiophene in the presence of CuI catalyst and N,N′-dimethylethylenediamine.(1)
  • As a ligand to synthesize the zirconium(IV) complex, Zr(MeC(O)NMe)4 by reacting with tetrakis(dimethylamido)zirconium.(2)



pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 1

flash_point_f

240.8 °F

flash_point_c

116 °C

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges



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Arend G Dijkstra et al.
The journal of physical chemistry. B, 115(18), 5392-5401 (2011-01-07)
The amide vibrational modes play an important role in energy transport and relaxation in polypeptides and proteins and provide us with spectral markers for structure and structural dynamics of these macromolecules. Here, we present a detailed model to describe the
Michael Harder et al.
ChemMedChem, 8(3), 397-404 (2013-01-29)
The less polar π-surface of protein amide groups is exposed in many receptor binding sites, either as part of the backbone or in Gln/Asn side chains. Using quantum chemical calculations and Protein Data Bank (PDB) searches on model systems, we
Hangfei Chen et al.
Environmental science & technology, 51(20), 11710-11717 (2017-09-15)
Amides represent an important class of nitrogen-containing compounds in the atmosphere that can in theory interact with atmospheric acidic particles and contribute to secondary aerosol formation. In this study, uptake coefficients (γ) of six alkylamides (C



Global Trade Item Number

SKUGTIN
M26305-500G04061834045830
M26305-100G04061834045823
M26305-5G04061832097466