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Merck
CN

M9265

1-Methyl-4-imidazoleacetic acid hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C6H8N2O2 · HCl
CAS Number:
Molecular Weight:
176.60
UNSPSC Code:
12352100
PubChem Substance ID:
EC Number:
252-577-5
MDL number:
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SMILES string

Cl.Cn1cnc(CC(O)=O)c1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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K Hartmann et al.
The journal of investigative dermatology. Symposium proceedings, 6(2), 143-147 (2002-01-05)
Mastcytosis is a rare disease characterized by an abnormal increase of mast cells in tissues. The skin is the organ most frequently involved, but mast cells also accumulate in the bone marrow, gastrointestinal tract, lymph nodes, spleen, and liver. Recent
Can urinary N-tele methylimidazoleacetic acid (t-MeImAA) serve as a marker of histaminergic activity in hepatic encephalopathy (HE)?
W A Fogel et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 51 Suppl 1, S63-S64 (2002-05-16)
Day-to-day variation in urinary excretion of the histamine metabolite methylimidazoleacetic acid.
G Granerus et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 47 Suppl 1, S52-S53 (1998-04-30)
S Bashir et al.
Alimentary pharmacology & therapeutics, 16(7), 1367-1382 (2002-07-30)
Chronic hypergastrinaemia causes gastric enterochromaffin cell proliferation and carcinoid tumours. The only reliable means to diagnose enterochromaffin cell changes/carcinoids is by biopsy. To assess whether serum histamine, chromogranin A or serotonin and urinary N-methylimidazoleacetic acid or 5-hydroxyindoleacetic acid correlate with
G D Prell et al.
Journal of neurochemistry, 67(5), 1938-1944 (1996-11-01)
Levels of histamine and its major metabolites in brain, tele-methylhistamine (t-MH) and tele-methylimidazoleacetic acid (t-MIAA), were measured in rat brains up to 12 h after intraperitoneal administration of L-histidine (His), the precursor of histamine. Compared with saline-treated controls, mean levels

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