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Merck
CN

P38706

Phthalazine

98%

Synonym(s):

β-Phenodiazine, 2,3-Benzodiazine, 2,3-Diazanaphthalene, Benzo[d]pyridazine

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About This Item

Empirical Formula (Hill Notation):
C8H6N2
CAS Number:
Molecular Weight:
130.15
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
205-963-2
MDL number:
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Product Name

Phthalazine, 98%

InChI key

LFSXCDWNBUNEEM-UHFFFAOYSA-N

InChI

1S/C8H6N2/c1-2-4-8-6-10-9-5-7(8)3-1/h1-6H

SMILES string

c1ccc2cnncc2c1

assay

98%

form

crystals

bp

189 °C/29 mmHg (lit.)

mp

89-92 °C (lit.)

storage temp.

2-8°C

Quality Level

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pictograms

Health hazard

signalword

Warning

hcodes

Hazard Classifications

Aquatic Chronic 3 - Muta. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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R S K Vijayan et al.
Journal of molecular graphics & modelling, 27(3), 286-298 (2008-06-21)
Given the heterogeneity of GABA(A) receptor, the pharmacological significance of identifying subtype selective modulators is increasingly being recognized. Thus, drugs selective for GABA(A) alpha(3) receptors are expected to display fewer side effects than the drugs presently in clinical use. Hence
Manuel Sánchez-Moreno et al.
Journal of medicinal chemistry, 55(22), 9900-9913 (2012-10-10)
A series of new phthalazine derivatives 1-4 containing imidazole rings were prepared. The monoalkylamino substituted derivatives 2 and 4 were more active in vitro against T. cruzi and less toxic against Vero cells than both their disubstituted analogues and the
Hyungchul Kim et al.
International journal of pharmaceutics, 377(1-2), 105-111 (2009-05-26)
Investigation of the use of solution NMR spectroscopy to determine the effect of organic solvents on chemical shift changes in bases on addition of acids is reported. This information can be useful in the evaluation of solvents and counterion selection
Kebin Li et al.
Analytical chemistry, 80(13), 4945-4950 (2008-05-30)
Arrays of Au nanowells (NWs) were fabricated by electron-beam lithography (EBL) and characterized by surface plasmon resonance (SPR) and surface-enhanced Raman scattering (SERS). It is revealed that these Au NW arrays exhibit multiple SP resonances that can be tuned by
Panayiotis A Procopiou et al.
Journal of medicinal chemistry, 54(7), 2183-2195 (2011-03-09)
A series of potent phthalazinone-based human H(1) and H(3) bivalent histamine receptor antagonists, suitable for intranasal administration for the potential treatment of allergic rhinitis, were identified. Blockade of H(3) receptors is thought to improve efficacy on nasal congestion, a symptom

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