QBD10204
TFP-dPEG®12-biotinidase resistant biotin
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About This Item
Empirical Formula (Hill Notation):
C47H76F4N4O17S
Molecular Weight:
1077.18
UNSPSC Code:
51171641
PubChem Substance ID:
NACRES:
NA.22
InChI key
NWCIJXJOOMRCER-UHFFFAOYSA-N
SMILES string
O=C1NC(C2N1)CSC2CCCCC(NC(C(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(OC3=C(C(F)=CC(F)=C3F)F)=O)=O)CC)=O
assay
>90%
form
solid or viscous liquid
reaction suitability
reagent type: cross-linking reagent
reaction type: Biotinylations
reactivity: amine reactive, reagent type: linker
polymer architecture
shape: linear
functionality: heterobifunctional
shipped in
ambient
storage temp.
−20°C
Related Categories
Features and Benefits
TFP-dPEG®12-biotinidase resistant biotin contains an amine reactive TFP ester and chemically modified biotin that is stable in the presence of biotinidase. Resistance to biotinidase cleavage of biotin is necessary in some biotechnology applications. The chemical modification to biotin imparts resistance to biotinidase cleavage without reducing the strength of biotin-avidin binding. The single molecular weight dPEG® spacer imparts water solubility, prevents aggregation and precipitation of labeled peptides and proteins, and reduces non-specific binding. Two different single molecular weight dPEG® spacers are available for precise spatial control between the modified biotin and the surface of the molecule to which it is conjugated.
Legal Information
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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