QBD10505
Azido-dPEG®12-NHS ester
Synonym(s):
Polyethylene glycol
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Empirical Formula (Hill Notation):
C31H56N4O16
Molecular Weight:
740.79
UNSPSC Code:
12352108
PubChem Substance ID:
NACRES:
NA.22
MDL number:
InChI key
JSNJRDFOCXNHTB-UHFFFAOYSA-N
SMILES string
O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])ON1C(CCC1=O)=O
assay
>90%
form
solid or viscous liquid
reaction suitability
reaction type: click chemistry, reagent type: cross-linking reagent
reaction type: click chemistry
polymer architecture
shape: linear
functionality: heterobifunctional
shipped in
ambient
storage temp.
−20°C
Features and Benefits
The azido-dPEG®12-NHS ester contains an azide function on one end of a single molecular weight dPEG® spacer (47.2 Å) and NHS ester group on the other end of the spacer. The dPEG® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. N-hydroxysuccinimide (NHS) ester readily reacts with amines in aqueous solution or organic solvent. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.
Legal Information
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service