QBD10514
Azido-dPEG®24-acid
Synonym(s):
Polyethylene glycol
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About This Item
Empirical Formula (Hill Notation):
C51H101N3O26
Molecular Weight:
1172.35
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.22
MDL number:
InChI key
DLBYIOOMXALGRA-UHFFFAOYSA-N
SMILES string
OC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O
assay
>90%
form
solid or viscous liquid
reaction suitability
reaction type: click chemistry, reagent type: cross-linking reagent
reaction type: click chemistry
polymer architecture
shape: linear
functionality: heterobifunctional
shipped in
ambient
storage temp.
−20°C
Features and Benefits
The azido-dPEG®24 contains an azide function on one end of a single molecular weight dPEG® spacer (90.4 Å) and a reactive group on the other end of the spacer. The dPEG® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The reactive acid functional group may be activated with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) or N,N′-dicyclohexylcarbodiimide (DCC) for conjugation to an amine. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.
Legal Information
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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