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Merck
CN

QBD10523

Azido-dPEG®7-amine

Synonym(s):

23-Azido-3,6,9,12,15,18,21-heptaoxatricosan-1-amine, Polyethylene glycol

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About This Item

Empirical Formula (Hill Notation):
C16H34N4O7
CAS Number:
1333154-77-0
Molecular Weight:
394.46
MDL number:
MFCD13185016
UNSPSC Code:
12352116
PubChem Substance ID:
329823937
NACRES:
NA.22

Key Documents

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Assay

>90%

form

solid or viscous liquid

reaction suitability

reaction type: click chemistry
reagent type: cross-linking reagent
reaction type: click chemistry

functional group

amine
azide

polymer architecture

shape: linear
functionality: heterobifunctional

shipped in

ambient

storage temp.

−20°C

SMILES string

NCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

InChI

1S/C16H34N4O7/c17-1-3-21-5-7-23-9-11-25-13-15-27-16-14-26-12-10-24-8-6-22-4-2-19-20-18/h1-17H2

InChI key

VZKXLNRXAFTBOW-UHFFFAOYSA-N

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Features and Benefits

The azido-dPEG®7-amine contains an azide function on one end of a single molecular weight dPEG® spacer (28.8 Å) and a reactive group on the other end of the spacer. The dPEG® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The amine group reacts with acids and active esters. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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