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Merck
CN

QBD10523

Azido-dPEG®7-amine

Synonym(s):

23-Azido-3,6,9,12,15,18,21-heptaoxatricosan-1-amine, Polyethylene glycol

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About This Item

Empirical Formula (Hill Notation):
C16H34N4O7
CAS Number:
1333154-77-0
Molecular Weight:
394.46
UNSPSC Code:
12352116
PubChem Substance ID:
329823937
NACRES:
NA.22
MDL number:
MFCD13185016

Key Documents

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InChI

1S/C16H34N4O7/c17-1-3-21-5-7-23-9-11-25-13-15-27-16-14-26-12-10-24-8-6-22-4-2-19-20-18/h1-17H2

InChI key

VZKXLNRXAFTBOW-UHFFFAOYSA-N

SMILES string

NCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

assay

>90%

form

solid or viscous liquid

reaction suitability

reaction type: click chemistry, reagent type: cross-linking reagent
reaction type: click chemistry

functional group

amine, azide

polymer architecture

shape: linear
functionality: heterobifunctional

shipped in

ambient

storage temp.

−20°C

Related Categories

Features and Benefits

The azido-dPEG®7-amine contains an azide function on one end of a single molecular weight dPEG® spacer (28.8 Å) and a reactive group on the other end of the spacer. The dPEG® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The amine group reacts with acids and active esters. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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