QBD10524
Azido-dPEG®11-amine
Synonym(s):
Polyethylene glycol
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About This Item
Empirical Formula (Hill Notation):
C24H50N4O11
Molecular Weight:
570.67
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.22
Assay
>90%
form
solid or viscous liquid
reaction suitability
reaction type: click chemistry
reagent type: cross-linking reagent
reaction type: click chemistry
polymer architecture
shape: linear
functionality: heterobifunctional
shipped in
ambient
storage temp.
−20°C
SMILES string
NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
InChI key
SEFFQZUNGHPPPA-UHFFFAOYSA-N
Features and Benefits
The azido-dPEG®11-amine contains an azide function on one end of a single molecular weight dPEG® spacer (44.2 Å) and a reactive group on the other end of the spacer. The dPEG® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The primary amine reactive group reacts with acids and active esters. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.
Legal Information
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class Code
11 - Combustible Solids
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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