QBD10869
Amino-dPEG®36-OH
>95% (HPLC)
Synonym(s):
Amino-PEG36-OH, Hydroxy-PEG-amine, Hydroxy-PEG36-amine, OH-PEG36-NH2, PEG1500-amine
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About This Item
Empirical Formula (Hill Notation):
C72H147NO36
Molecular Weight:
1602.92
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.22
Assay
>95% (HPLC)
form
solid or viscous liquid
reaction suitability
reaction type: Pegylations
polymer architecture
shape: linear
functionality: heterobifunctional
shipped in
ambient
storage temp.
−20°C
SMILES string
NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
InChI key
MAESJFAEMPPQIN-UHFFFAOYSA-N
Features and Benefits
Amino-dPEG36-OH, also known as Amino-dPEG36-alcohol, is a very long (109 atoms, 127.7 Å) monodispersed PEGylation reagent functionalized with a primary amine on one end of the molecule that reacts with carboxylic acids, aldehydes, and ketones. Reacting the amine group with carboxylic acids yields stable amides while reacting the amine group with aldehydes and ketones forms Schiff bases that are reducible to secondary amines for stability. If needed, various functional and reactive groups can modify the terminal alcohol on the opposite end of the molecule to provide the dPEG product with additional reactivity or crosslinking capability. dPEG36 is a monodisperse equivalent of the polymeric PEG1500. Amino-dPEG36-OH can be used for passivation of carboxylate-functionalized surfaces. The non-immunogenic terminal alcohol of the PEG chain imparts hydrophilicity to the conjugate molecule or surface. Consequently, conjugate molecules are water-soluble.
Legal Information
Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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