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Merck
CN

T111

8-(Diethylamino)octyl-3,4,5-trimethoxybenzoate hydrochloride

≥98%

Synonym(s):

TMB 8 hydrochloride, TMB-8 · HCl

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About This Item

Linear Formula:
(CH3O)3C6H2CO2(CH2)8N(C2H5)2 · HCl
CAS Number:
53464-72-5
Molecular Weight:
431.99
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
57654652
EC Number:
258-574-5
Beilstein/REAXYS Number:
5466611
MDL number:
MFCD00012502
Assay:
≥98%
Form:
powder

Key Documents

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Product Name

8-(Diethylamino)octyl-3,4,5-trimethoxybenzoate hydrochloride, ≥98%

InChI

1S/C22H37NO5.ClH/c1-6-23(7-2)14-12-10-8-9-11-13-15-28-22(24)18-16-19(25-3)21(27-5)20(17-18)26-4;/h16-17H,6-15H2,1-5H3;1H

InChI key

KFJZVXKPPQIYCG-UHFFFAOYSA-N

SMILES string

Cl[H].CCN(CC)CCCCCCCCOC(=O)c1cc(OC)c(OC)c(OC)c1

assay

≥98%

form

powder

mp

94-97 °C (lit.)

Quality Level

100

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Application

  • Pharmacologically active inhibitor of hepatitis C virus life cycle

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Hai-Long Wang et al.
The Chinese journal of physiology, 55(2), 101-107 (2012-05-09)
The purpose of this study was to determine the effects of an extract from Moringa oleifera (MO) on the development of monocrotaline (MCT)-induced pulmonary hypertension (PH) in Wistar rats. An ethanol extraction was performed on dried MO leaves, and HPLC
Patrycja Libako et al.
Magnesium research, 25(1), 12-20 (2012-03-30)
Divalent cations, especially calcium and magnesium, have been shown to play an important regulatory role in endothelial and immune cells. To learn more about the interaction of these two metals in the regulation of cell growth, we altered the calcium/magnesium
Byung-Hwan Lee et al.
Biological & pharmaceutical bulletin, 32(5), 861-867 (2009-05-08)
Previous reports have shown that diltiazem and TMB, calcium channel antagonists, inhibit 5-hydroxytryptamine type 3A (5-HT(3A)) receptor-mediated currents (I(5-HT)) in cell lines and in heterologously expressed Xenopus oocytes. In the present study, we sought to elucidate the molecular mechanisms underlying
A Ruiz et al.
Cell death & disease, 1, e54-e54 (2011-03-03)
Overactivation of ionotropic glutamate receptors in oligodendrocytes induces cytosolic Ca(2+) overload and excitotoxic death, a process that contributes to demyelination and multiple sclerosis. Excitotoxic insults cause well-characterized mitochondrial alterations and endoplasmic reticulum (ER) dysfunction, which is not fully understood. In
Maria Luisa Zaccardi et al.
Behavioural brain research, 229(1), 235-243 (2012-01-31)
Although habituation is ubiquitous in the animal kingdom, its underlying mechanisms remain poorly understood. In this study, we began to explore the molecular cascades underlying short-term habituation in the leech Hirudo medicinalis. In H. medicinalis, a training paradigm, consisting of
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