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Merck
CN

T1388

2-Thiophenecarboxylic acid hydrazide

≥98%

Synonym(s):

2-Thenoylhydrazine, 2-Thienoylhydrazine, 2-Thienyl hydrazide, 2-Thienylcarboxylic acid hydrazide, 2-Thiophenecarbohydrazonic acid, 2-Thiophenecarbonyl hydrazide, 2-Thiophenecarboxylic hydrazide, Thiophene-2-carbohydrazide

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About This Item

Empirical Formula (Hill Notation):
C5H6N2OS
CAS Number:
2361-27-5
Molecular Weight:
142.18
NACRES:
NA.22
PubChem Substance ID:
57654655
UNSPSC Code:
12352100
EC Number:
219-107-0
MDL number:
MFCD00005435

Key Documents

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Product Name

2-Thiophenecarboxylic acid hydrazide, ≥98%

InChI key

SOGBOGBTIKMGFS-UHFFFAOYSA-N

InChI

1S/C5H6N2OS/c6-7-5(8)4-2-1-3-9-4/h1-3H,6H2,(H,7,8)

SMILES string

NNC(=O)c1cccs1

assay

≥98%

form

powder

mp

136-139 °C (lit.)

Quality Level

200

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pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN5546
BCCL9849
BCCK7744
BCCK0027
BCCH4760

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Sherry L Kurtz et al.
mSphere, 5(2) (2020-04-17)
Many studies of Mycobacterium tuberculosis infection and immunity have used mouse models. However, outcomes of vaccination and challenge with M. tuberculosis in inbred mouse strains do not reflect the full range of outcomes seen in people. Previous studies indicated that
Jaehun Park et al.
Virulence, 11(1), 430-445 (2020-05-15)
Toll-like receptors (TLRs) play critical roles in the innate recognition of Mycobacterium tuberculosis (Mtb) by host immune cells. However, controversy has arisen regarding the role of TLR4 in determining the outcomes of Mtb infection. To address this controversy, the function
J I Moliva et al.
Mucosal immunology, 11(3), 968-978 (2017-09-21)
Current tuberculosis (TB) treatments include chemotherapy and preventative vaccination with Mycobacterium bovis Bacillus Calmette-Guérin (BCG). In humans, however, BCG vaccination fails to fully protect against pulmonary TB. Few studies have considered the impact of the human lung mucosa (alveolar lining
M D Yates et al.
Tubercle, 65(4), 295-299 (1984-12-01)
Thiophen-2-carboxylic acid hydrazide (TCH) is used to distinguish TCH-sensitive bovine, 'Asian human' and 'African' strains from TCH-resistant 'classical' human strains of Mycobacterium tuberculosis. It has been claimed that this test cannot be applied to isoniazid-resistant strains as these also become
Harindra D Sathkumara et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(34), 20848-20859 (2020-08-12)
Tuberculosis (TB) claims 1.5 million lives per year. This situation is largely due to the low efficacy of the only licensed TB vaccine, Bacillus Calmette-Guérin (BCG) against pulmonary TB. The metabolic disease type 2 diabetes (T2D) is a risk factor
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