T33553
Thiourea
99%
Synonym(s):
Sulfourea, Thiocarbamide
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About This Item
Linear Formula:
NH2CSNH2
CAS Number:
Molecular Weight:
76.12
EC Number:
200-543-5
UNSPSC Code:
12352103
PubChem Substance ID:
Beilstein/REAXYS Number:
605327
MDL number:
assay
99%
mp
170-176 °C (lit.)
SMILES string
NC(N)=S
InChI
1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)
InChI key
UMGDCJDMYOKAJW-UHFFFAOYSA-N
Application
Chaotropic agent; strong denaturant. Increases solubility and recovery of proteins
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Regulatory Information
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Gang Liu et al.
Nature chemistry, 5(12), 1049-1057 (2013-11-22)
With the intention of improving synthetic efficiency, organic chemists have turned to bioinspired organocascade or domino processes that generate multiple bonds and stereocentres in a single operation. However, despite the great importance of substituted cyclopentanes, given their prevalence in complex
Yoshiji Takemoto
Chemical & pharmaceutical bulletin, 58(5), 593-601 (2010-05-13)
We have developed several multifunctional thiourea catalysts bearing a tertiary amine or an 1,2-amino alcohol in expectation of their synchronous activation of a nucleophile and an electrophile through both acid-base and hydrogen-bonding interactions. From these studies, it was revealed that
Dhivya R Sudhan et al.
Clinical & experimental metastasis, 30(7), 891-902 (2013-06-12)
Metastasis remains the major cause of therapeutic failure, poor prognosis and high mortality in breast and prostate cancer patients. Aberrant microenvironments including hypoxia and acidic pH are common features of most solid tumors that have been long associated with enhanced