T70408
3,4,5-Trimethoxycinnamic acid
97%
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About This Item
Linear Formula:
(CH3O)3C6H2CH=CHCO2H
CAS Number:
Molecular Weight:
238.24
UNSPSC Code:
12352100
PubChem Substance ID:
EC Number:
201-999-8
MDL number:
Assay:
97%
InChI key
YTFVRYKNXDADBI-SNAWJCMRSA-N
InChI
1S/C12H14O5/c1-15-9-6-8(4-5-11(13)14)7-10(16-2)12(9)17-3/h4-7H,1-3H3,(H,13,14)/b5-4+
SMILES string
COc1cc(\C=C\C(O)=O)cc(OC)c1OC
assay
97%
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Sarvesh Kumar et al.
Biochemistry, 44(48), 15944-15952 (2005-11-30)
We report here the isolation and characterization of two active principles, ethyl 3',4',5'-trimethoxycinnamate (1) and piperine (2), from the combined hexane and chloroform extracts of Piper longum. Using primary human umbilical vein endothelial cells, we evaluated the activities of compound
Zhenghang Zhao et al.
Biological & pharmaceutical bulletin, 36(2), 238-244 (2012-12-01)
3,4,5-Trimethoxycinnamic acid (TMCA), methyl 3,4,5-trimethoxycinnamate (M-TMCA) and p-methoxycinnamic acid (PMCA) have been identified as the major bioactive components in the serum collected from rats treated with oral administration of Polygalae Radix ("YuanZhi," the roots of Polygala tenuifolia WILLD.), a traditional
Yingming Wu et al.
Organic letters, 11(3), 597-600 (2008-12-25)
A highly flexible and concise total synthesis of (+)-podophyllotoxin featured with an enantioselective sequential conjugate addition-allylation reaction was reported. Starting from commercially available 3,4,5-trimethoxycinnamic acid, this new route leads to (+)-podophyllotoxin 1 in only eight steps with 29% overall yield.
Keiko Kawashima et al.
Biological & pharmaceutical bulletin, 27(8), 1317-1319 (2004-08-12)
3,4,5-trimethoxycinnamic acid (TMCA) is one of the constituents in Onji (roots of Polygala tenuifolia WILLD), an herbal medicine used for sedative in Japanese traditional Kampo medicine. Our previous study revealed that oral administration of this compound prolongs sleeping time induced
M I Donnelly et al.
Journal of bacteriology, 147(2), 471-476 (1981-08-01)
When grown on 3,4,5-trimethoxycinnamic acid, a strain of Pseudomonas putida oxidized this compound and also 3,4,5-trimethoxybenzoic, 3,5-dimethoxy-4-hydroxybenzoic (syringic), and 3,4-dihydroxy-5-methoxybenzoic (3-O-methylgallic) acids, but 3,5-dimethoxy-4-hydroxycinnamic and other acids bearing structural resemblances to the growth substrate were oxidized only slowly. These results
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