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About This Item
Linear Formula:
NH2CONH2
CAS Number:
Molecular Weight:
60.06
EC Number:
200-315-5
UNSPSC Code:
12352103
MDL number:
Beilstein/REAXYS Number:
635724
InChI
1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)
InChI key
XSQUKJJJFZCRTK-UHFFFAOYSA-N
SMILES string
NC(N)=O
grade
ACS reagent
assay
≥99%, 99.0-100.5%
impurities
≤0.01% insolubles
ign. residue
≤0.01%
density
1.335 g/mL at 25 °C (lit.)
anion traces
chloride (Cl-): ≤5 ppm, sulfate (SO42-): ≤0.001%
cation traces
Fe: ≤0.001%, heavy metals: ≤0.001%
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Application
Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Chuanyu Yang et al.
PloS one, 10(7), e0133826-e0133826 (2015-07-25)
Huanglongbing (HLB) is the most serious disease affecting the citrus industry worldwide to date. The causal agent, Candidatus Liberibacter asiaticus (Las), resides in citrus phloem, which makes it difficult to effectively treat with chemical compounds. In this study, a transcuticular
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