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Merck
CN

W233609

Costus oil

natural, FG

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About This Item

CAS Number:
FEMA Number:
2336
UNSPSC Code:
12164502
EC Number:
290-278-1
NACRES:
NA.21
MDL number:
Organoleptic:
woody; animal
Grade:
FG
Kosher
natural
Biological source:
Saussurea lappa Clarke
Food allergen:
no known allergens
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Product Name

Costus oil, natural, FG

Quality Level

biological source

Saussurea lappa Clarke

grade

FG
Kosher
natural

reg. compliance

EU Regulation 1334/2008 & 178/2002
FDA 21 CFR 117
FDA 21 CFR 172.510

origin

France origin

refractive index

n20/D 1.5180 (lit.)

density

1.002 g/mL at 25 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

woody; animal

Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Regulatory Information

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I Takanami et al.
Gan no rinsho. Japan journal of cancer clinics, 29(11), 1319-1322 (1983-09-01)
Delayed hypersensitivity skin responses to costus root oil were measured in patients with colon, stomach, breast and lung cancer and in healthy controls. Cancer patients were staged according to tumor spread. Differences were demonstrated between cancer patients and controls. Patients
Occupational erythema-multiforme-like dermatitis from sensitization to costus resinoid, followed by flare-up and systemic contact dermatitis from beta-cyclocostunolide in a chemistry student.
C J Le Coz et al.
Contact dermatitis, 44(5), 310-311 (2001-05-31)
S Schauder
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society, 9(3), 182-187 (1998-09-24)
Although photosensitivity after photoallergy to topical phenothiazine antihistamines is well known, there have been no previous reports of dioxopromethazine inducing this phenomenon. A housewife used 0.5% dioxopromethazine in Prothanon gel for palpebral pruritus and developed severe dermatitis of the lower
I Takanami et al.
Gan to kagaku ryoho. Cancer & chemotherapy, 11(1), 81-86 (1984-01-01)
Costus root oil is a new primary sensitizer to examine the delayed, cell-mediated immune system. The peripheral blood lymphocyte count has been measured in 68 cases of carcinoma of the stomach and colon. The count has been correlated with the
Methyl ester of para-coumaric acid: antifungal principle of the rhizome of Costus speciosus.
B M Bandara et al.
Planta medica, 54(5), 477-478 (1988-10-01)

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