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Merck
CN

W245704

Ethyl pyruvate

≥97%

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About This Item

Linear Formula:
CH3COCOOC2H5
CAS Number:
Molecular Weight:
116.12
PubChem Substance ID:
UNSPSC Code:
12164502
Council of Europe no.:
430
FEMA Number:
2457
Flavis number:
9.442
EC Number:
210-511-2
MDL number:
Beilstein/REAXYS Number:
1071466
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InChI key

XXRCUYVCPSWGCC-UHFFFAOYSA-N

InChI

1S/C5H8O3/c1-3-8-5(7)4(2)6/h3H2,1-2H3

SMILES string

CCOC(=O)C(C)=O

biological source

synthetic

grade

Halal

reg. compliance

FDA 21 CFR 172.515

assay

≥97%

refractive index

n20/D 1.404 (lit.)

bp

144 °C (lit.)

density

1.045 g/mL at 25 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

ethereal; vegetable; fruity; rum; sweet

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pictograms

FlameCorrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

114.8 °F - closed cup

flash_point_c

46 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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Runkuan Yang et al.
Critical care (London, England), 16(1), R9-R9 (2012-01-18)
Inflammation may critically affect mechanisms of liver injury in acetaminophen (APAP) hepatotoxicity. Kupffer cells (KC) play important roles in inflammation, and KC depletion confers protection at early time points after APAP treatment but can lead to more severe injury at
Zheng-Gang Luan et al.
The Journal of surgical research, 181(1), 76-84 (2012-06-22)
Systemic inflammatory mediators have an important role in the development of acute pancreatitis. In this study, we investigated the effect of ethyl pyruvate (EP) on pancreas injury in rats with severe acute pancreatitis (SAP) and its possible mechanism. We randomly allocated
Yimin Yuan et al.
British journal of pharmacology, 166(2), 749-763 (2011-12-07)
Spinal cord injury (SCI) triggers a series of endogenous processes, including neuroinflammation and reactive astrogliosis, which may contribute to the failure of neural regeneration and functional recovery. In the present study, the effect of ethyl pyruvate on spinal cord repair
M-L Li et al.
International journal of immunopathology and pharmacology, 25(4), 955-965 (2013-01-10)
High mobility group box B1 (HMGB1)-receptor for advanced glycation end products (RAGE) axis has been previously known to be involved in carcinogenesis and development of multiple malignancies. Some studies have confirmed that Ethyl pyruvate (EP), a potent inhibitor of HMGB1
T J Percival et al.
The British journal of surgery, 99 Suppl 1, 66-74 (2012-03-28)
Extremity injury with ischaemia is the most common pattern of vascular trauma and is a challenge for surgeons who must make decisions about the timing and mechanism of limb reperfusion. In modern military conflicts, effective use of limb tourniquets and

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