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Sigma-Aldrich

Methyl palmitate

≥97%

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Synonym(s):
n-Hexadecanoic acid methyl ester, Methyl hexadecanoate, Palmitic acid methyl ester
Linear Formula:
CH3(CH2)14CO2CH3
CAS Number:
112-39-0
Molecular Weight:
270.45
Beilstein:
1780973
EC Number:
203-966-3
Council of Europe no.:
581
MDL number:
MFCD00008994
PubChem Substance ID:
24902044
Flavis number:
9.180
NACRES:
NA.21

biological source

Cocos nucifera
palm oil
synthetic

Quality Level

400

Assay

≥97%

refractive index

n20/D 1.4512 (lit.)

bp

185 °C/10 mmHg (lit.)

mp

32-35 °C (lit.)

density

0.852 g/mL at 25 °C (lit.)

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

tree nuts

Organoleptic

waxy

SMILES string

CCCCCCCCCCCCCCCC(=O)OC

InChI

1S/C17H34O2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17(18)19-2/h3-16H2,1-2H3

InChI key

FLIACVVOZYBSBS-UHFFFAOYSA-N

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General description

Methyl palmitate is a fatty acid methyl ester (FAME) that occurs naturally in crude palm oil and walnut.

Application

Methyl palmitate can be used as an additive in food and cosmetic industries for the stabilization of fats and oil products by slowing down the auto-oxidation of unsaturated fatty acids.

Biochem/physiol Actions

Methyl palmitate has anti-inflammatory and anti-fibrotic effect. Methyl palmitate prevents bleomycin-induced lung inflammation and fibrosis in rats, by inhibiting NF-κB . Methyl palmitate also prevents CCl4-induced liver fibrosis linked to reduced TGF-β .

Disclaimer

For R&D or non-EU Food use. Not for retail sale.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113.0 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Solvent free synthesis of methyl palmitate over sulfated zirconia solid acid catalyst
Saravanan K, et al.
Fuel: The Science and Technology of Fuel and Energy, 165(11), 298-305 (2016)
Biodiesel production from crude Jatropha curcas L. seed oil with a high content of free fatty acids.
Berchmans HJ & Hirata S.
Bioresource Technology, 99(6), 1716-1721 (2008)
Density and speed of sound measurements on five fatty acid methyl esters at 83 kPa and temperatures from (278.15 to 338.15) K.
Ott LS, et al.
Journal of Chemical and Engineering Data, 53(10), 2412-2416 (2008)
Enzyme catalyzed synthesis of cosmetic esters and its intensification: A review
Khan NR and Rathod VK
Process. Biochem., 50(11), 1793-1806 (2015)
Markus Rentsch et al.
Transplant international : official journal of the European Society for Organ Transplantation, 18(9), 1079-1089 (2005-08-17)
Inhibition or destruction of Kupffer cells (KC) may protect against ischemia-reperfusion (IR) induced primary graft nonfunction (PNF) in liver transplantation. Besides KC activation, PNF is characterized by microvascular perfusion failure, intrahepatic leukocyte accumulation, cell death and hepatocellular dysfunction. KCs can
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