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Merck
CN

W778893

Sigma-Aldrich

α-Cyclodextrin

FG, produced by Wacker Chemie AG, Burghausen, Germany, Food

Synonym(s):

β-CD, Cavamax® W6, α-Schardinger dextrin, Cyclohexaamylose, Cyclomaltohexaose

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About This Item

Empirical Formula (Hill Notation):
C36H60O30
CAS Number:
10016-20-3
Molecular Weight:
972.84
Beilstein:
79627
EC Number:
233-007-4
MDL number:
MFCD00078207
UNSPSC Code:
12164502
PubChem Substance ID:
329830760
NACRES:
NA.21

Key Documents

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grade

FG

reg. compliance

EU Regulation 178/2002

description

derived from GMO corn

impurities

≤0.5% reducing substances (determined as dextrose)
≤20 ppm volatile organics
≤5 ppm heavy metals
0 Salmonella/E.Coli in 10 g

ign. residue

≤0.1%

loss

≤11% loss on drying

mp

>278 °C (dec.) (lit.)

cation traces

As: ≤1.3 ppm
Pb: ≤0.5 ppm

application(s)

flavors and fragrances

food allergen

no known allergens

Organoleptic

odorless

SMILES string

OC[C@H]1O[C@@H]2O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3CO)O[C@H]4[C@H](O)[C@@H](O)[C@H](O[C@@H]4CO)O[C@H]5[C@H](O)[C@@H](O)[C@H](O[C@@H]5CO)O[C@H]6[C@H](O)[C@@H](O)[C@H](O[C@@H]6CO)O[C@H]7[C@H](O)[C@@H](O)[C@H](O[C@@H]7CO)O[C@H]1[C@H](O)[C@H]2O

InChI

1S/C36H60O30/c37-1-7-25-13(43)19(49)31(55-7)62-26-8(2-38)57-33(21(51)15(26)45)64-28-10(4-40)59-35(23(53)17(28)47)66-30-12(6-42)60-36(24(54)18(30)48)65-29-11(5-41)58-34(22(52)16(29)46)63-27-9(3-39)56-32(61-25)20(50)14(27)44/h7-54H,1-6H2/t7-,8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-/m1/s1

InChI key

HFHDHCJBZVLPGP-RWMJIURBSA-N

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General description

α-Cyclodextrin (α-CD) is a cyclic oligosaccharide that consists of six glucopyranose units linked by α-(1,4) bonds. It can form a stable complex with dietary fat, which is resistant to lipolytic hydrolysis and is excreted intact leading to weight loss.

Application

α-CD can act as a stabilizer for emulsions such as mayonnaise, margarine or butter creams. The addition of α-CD (5-10%) to soy protein hydrolysate solution led to a decrease in its bitterness due to the formation of inclusion complexes with its amino acids.

Legal Information

Cavamax is a registered trademark of Wacker Chemie AG

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Precautionary Statements

P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
STBJ4673
STBJ4168
STBF1244V
STBD0078
STBD4112V

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Cyclodextrins and their uses: a review
Del Valle EMM
Process. Biochem., 39(9), 1033-1046 (2004)
Taste modification of amino acids and protein hydrolysate by a-cyclodextrin
Linde GA, et al.
Food Research International, 42(7), 814-818 (2009)
The Beneficial Effects a-Cyclodextrin on Blood Lipids and Weight Loss in Healthy Humans
Comerford KB, et al
Obesity (Silver Spring, Md.), 19(6), 1200-1204 (2011)
Hidetoshi Arima et al.
Molecular pharmaceutics, 9(9), 2591-2604 (2012-08-10)
We previously reported that of the various polyamidoamine (PAMAM) STARBURST dendrimer (generation 3, G3) (dendrimer) conjugates with cyclodextrins (CyDs), the dendrimer (G3) conjugate with α-CyD having an average degree of substitution of 2.4 (α-CDE (G3)) has the greatest potential for
Yi Zhou et al.
Molecular pharmaceutics, 9(5), 1067-1076 (2012-04-10)
Safe and effective gene delivery is essential to the success of gene therapy. We synthesized and characterized a novel nonviral gene delivery system in which folate (FA) molecules were functioned as blockers on cationic polyrotaxanes (PR) composed of poly(ethylenimine) (PEI)(600)-grafted
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